Protein Alignment Cyp4a14 and Cyp4d8

DIOPT Version :9

• Sequence 1: NP_031848.1
• Gene: Cyp4a14 / 13119
• MGIID: 1096550
• Length: 507
• Species: Mus musculus
• Sequence 2: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Alignment Length: 505
• Identity: 154/505 - (30%)
• Similarity: 253/505 - (50%)
• Gaps: 72/505 - (14%)

Mouse    31 LFKAVQFYLR----------RQWLLKTLQHFPCMPSHWLWGHHLKDKELQQILIWVEKFPSACLQ 85
            |..|:|..||          |:::||             :||      ||::.|:..      |.
  Fly    39 LIGAMQLMLRLNPKTFIKVGREYVLK-------------FGH------LQRVWIFNR------LL 78

Mouse    86 CLSGS---NIRVLLYDPDYVKVVLGRSDPKASGIYQFFAPWIGYGLLLLNGKKWFQHRRMLTPAF 147
            .:||.   |.::|......||          ..:|:....|:|.||||.:||.|.|.|:::||.|
  Fly    79 IMSGDAELNEQLLSSQEHLVK----------HPVYKVLGQWLGNGLLLSDGKVWHQRRKIITPTF 133

Mouse   148 HYDILKPYVKIMADSVNIMLDKW-EKLDGQDHPLEIFHCVSLMTLDTVMKCAFSYQGSVQLDENS 211
            |:.||:.:|::.....||.:.:. :|.:|  :..:::..:....||.:.:.|...:...|.:|::
  Fly   134 HFSILEQFVEVFDQQSNICVQRLAQKANG--NTFDVYRSICAAALDIIAETAMGTKIYAQANEST 196

Mouse   212 KLYTKAVEDLNNLTFFRLRNAFYKYNIIYNMSSDGRLSHHACQI---AHEHTDGVIKMRKSQLQN 273
            . |.:||.:...|..:|..:.:.:..:::.::.. .|.....|:   ..|.|..||:.|:..|::
  Fly   197 P-YAEAVNECTALLSWRFMSVYLQVELLFTLTHP-HLKWRQTQLIRTMQEFTIKVIEKRRQALED 259

Mouse   274 EEEL------QKARKKRHLDFLDILLFARMEDRNSLSDEDLRAEVDTFMFEGHDTTASGISWIFY 332
            ::..      :....||.:..||:||.:.::.| .|:::::|.|||||||||||||.|.:|:..:
  Fly   260 QQSKLMDTADEDVGSKRRMALLDVLLMSTVDGR-PLTNDEIREEVDTFMFEGHDTTTSALSFCLH 323

Mouse   333 ALATHPEHQQRCREEVQSILGDGTS--VTWDHLGQMPYTTMCIKEALRLYPPVISVSRELSSPVT 395
            .|:.|||.|.:..||:..:||...|  |:...||::.|....|||:||:||||..|.|:|.:...
  Fly   324 ELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESLRMYPPVPIVGRKLQTDFK 388

Mouse   396 FP-----DGRSIPKGITATISIYGLHHNPRFWPNPKVFDPSRFAPDSSHHSHAYLPFSGGSRNCI 455
            :.     || .||.|....|.|:|:|..|..:|||..|.|.|....|.......:|||.|.||||
  Fly   389 YTHSVHGDG-VIPAGSEIIIGIFGVHRQPETFPNPDEFIPERHENGSRVAPFKMIPFSAGPRNCI 452

Mouse   456 GKQFAMNELKVAVALTLLRFELLPDPTRIPVPIARLVLKSKNGIHLCLKK 505
            |::||..|:|:.:|..:..:||||...|:.. |..:||:|:.|..|.::|
  Fly   453 GQKFAQLEMKMMLAKIVREYELLPMGQRVEC-IVNIVLRSETGFQLGMRK 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4a14	NP_031848.1	p450	52..501	CDD:278495	144/468 (31%)
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	144/459 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845059
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750