Protein Alignment Cyp4a14 and Cyp316a1

DIOPT Version :9

• Sequence 1: NP_031848.1
• Gene: Cyp4a14 / 13119
• MGIID: 1096550
• Length: 507
• Species: Mus musculus
• Sequence 2: NP_648129.2
• Gene: Cyp316a1 / 38840
• FlyBaseID: FBgn0035790
• Length: 484
• Species: Drosophila melanogaster
• Alignment Length: 524
• Identity: 130/524 - (24%)
• Similarity: 222/524 - (42%)
• Gaps: 100/524 - (19%)

Mouse    12 LDGISGFFQWAFLLSLFLVLF-KAVQFYLR-RQWLLKTLQHFPCMPSHWLWGHH-----LKDKEL 69
            :..:.|.|.|..:.::..:|| ..:.|:.| .::|.|......|      |..|     |.|.||
  Fly    28 IKNLKGPFTWPLMGAMHKLLFLTPINFFQRSTEYLTKYGTFSRC------WVFHRLFIPLADLEL 86

Mouse    70 QQILIWVEKFPSACLQCLSGSNIRVLLYDPDYVKVVLGRSDPKASGIYQFFAPWIGYGLLLLNGK 134
            .:.|:                                 .:|......|:....|:..|:|:...:
  Fly    87 SRQLL---------------------------------ENDTHLETGYELMKDWLVGGVLMCQSE 118

Mouse   135 KWFQHRRMLTPAFHYDILKPYVKIMADSVNIMLDKWEKLDGQDHPLEIFHCVSLMTLDTVMKCAF 199
            :|.:...:::..|....|:..:.:.......:|.|..| .......:|::.||.:.||.::....
  Fly   119 QWQKRHSLISGLFDKGNLEQLIDLSRHQTEQLLQKLAK-QADQKVFDIWYTVSPIVLDLMVMTTC 182

Mouse   200 SYQGSVQLDENSKLYTKAVEDLNNL---TFFRLRNAFYKYNIIYNMSSD---GRLSHHACQIAHE 258
            ..:.|.:       |:|.::||:.:   .|..|::| .::|  |.:||.   .|.:....::..|
  Fly   183 GAKPSEE-------YSKNLKDLSEIYRKRFLSLQSA-NRFN--YWLSSPFMRKRQNRLIKRLNDE 237

Mouse   259 HTDGVIKMRKSQ----LQNEEELQKARK---KRHLDFLDILLFARMEDRN-SLSDEDLRAEVDTF 315
            | :.::.|.:||    ::|..::.:.|.   |.|...|:|||    |.:: .|:.|::..|::|.
  Fly   238 H-NNLMAMHQSQNQLKIENGLDIYQLRPIPLKDHKSLLEILL----ESKDPQLTGEEICGELNTC 297

Mouse   316 MFEGHDTTASGISWIFYALATHPEHQQRCREEVQ--SILGDGTSVTWDHLGQMPYTTMCIKEALR 378
            .:.|:...:..:.:....:|.:|..||:|.:|:.  .|...|    || |.::.|....:.|.:|
  Fly   298 NYLGYQLCSPALCFCLVTIARNPSVQQKCLDELNLAQIKDQG----WD-LEKLNYLDAVLHETMR 357

Mouse   379 LYPPVISVSRELSSPVTFPDGRSI------PKGITATISIYGLHHNPRFWPNPKVFDPSRFAPDS 437
            ||||.:.|.|:|..  .||...||      |.|....|::|.|..|...:|....||..||. ||
  Fly   358 LYPPQVIVGRQLKK--DFPYTHSIVGDAELPCGSEIYINLYELQRNEVRYPKANHFDAQRFL-DS 419

Mouse   438 SHHSHAYLPFSGGSRNCIGKQFAMNELKVAVALTLLRFELLP--DPTRIPVPIARLVLKSKNGIH 500
            ...   .|.:|.|.|.|..::|:|..||..:|..|..||:||  |..|:.:   ||||.|.||..
  Fly   420 PPE---LLSYSLGPRCCPARKFSMQLLKTLLAPILANFEVLPYGDEVRLDL---RLVLGSSNGFQ 478

Mouse   501 LCLK 504
            |.||
  Fly   479 LALK 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4a14	NP_031848.1	p450	52..501	CDD:278495	118/477 (25%)
Cyp316a1	NP_648129.2	p450	33..466	CDD:299894	120/498 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820