Protein Alignment Cyp4a14 and Cyp6a21

DIOPT Version :9

• Sequence 1: NP_031848.1
• Gene: Cyp4a14 / 13119
• MGIID: 1096550
• Length: 507
• Species: Mus musculus
• Sequence 2: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0033981
• Length: 504
• Species: Drosophila melanogaster
• Alignment Length: 520
• Identity: 113/520 - (21%)
• Similarity: 213/520 - (40%)
• Gaps: 69/520 - (13%)

Mouse    26 SLFLVLFKAVQFYLRRQWLLKTLQHF-----PCMPSHWLWGHHLKDKELQQIL--IWV---EKF- 79
            ::.|....|:..||..:| ..|::|:     ||...|.|.| .:|.....:..  ||.   .||
  Fly     5 TVLLTALLALVGYLLMKW-RSTMRHWQDLGIPCEEPHILMG-SMKGVRTARSFNEIWTSYYNKFR 67

Mouse    80 ---PSACLQCLSGSNIRVLLYDPDYVKVVLGRSDPKASGIYQFFAPW---IGYGLLLLNGKKWFQ 138
               |.|.........:.||  :....|.:|.:...|.:....|..|.   :...|.||:|:||..
  Fly    68 GSGPFAGFYWFRRPAVFVL--ETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQLFLLDGQKWRT 130

Mouse   139 HRRMLTPAFHYDILKPYVKIMADSVNIMLDKWEKLDGQDHPLEIFHCVSLMTLDTVMKCAFSYQG 203
            .|..|:..|....:|.....:....|...|.:.:...:...:|:...::..|.|.:..|||..:.
  Fly   131 MRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVRELLARFTTDVIGTCAFGIEC 195

Mouse   204 SVQLDENSKLYTKAVEDLNNLTFFRLRNAFYKYNIIYNMSSDGRLSHHACQIAHEHTDGVIKMRK 268
            |...|.:::.     .::...:....|........:.:..:..|..|             :||..
  Fly   196 SSLKDPDAEF-----REMGRRSLTEQRLGPVGIGFVNSFPNLARRLH-------------MKMTA 242

Mouse   269 SQLQN-----EEELQKARKKRHL---DFLD--------ILLFARMEDRNSLSDEDLRAEVDTFMF 317
            ..::.     ..|....|::.::   ||:|        .|:.::..:..:|:.|::.|:...|..
  Fly   243 EPIERFFMRIVRETVAFREQNNIRRNDFMDQLIDLKNKPLMVSQSGESVNLTIEEIAAQAFVFFA 307

Mouse   318 EGHDTTASGISWIFYALATHPEHQQRCREEVQSIL----GDGTSVTWDHLGQMPYTTMCIKEALR 378
            .|.:|:::.:.:..|.||.:.:.|.|.|:|.|.::    |:   :.::.:..:.|....:.|.||
  Fly   308 AGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGE---LNYESMKDLVYLDQVVSETLR 369

Mouse   379 LYPPVISVSRELSSPVTFPDGRS--IPKGITATISIYGLHHNPRFWPNPKVFDPSRFAPD--SSH 439
            ||..:..::||.......|....  |.||:...|....:|.:.:.:.||..|:|..|:|:  ...
  Fly   370 LYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKER 434

Mouse   440 HSHAYLPFSGGSRNCIGKQFAMNELKVAVALTLLRFEL-LPDPTRIPVPIAR--LVLKSKNGIHL 501
            .|..:|||..|.|||||.:|...:.::.:||.:..|:. :.:.|.||:...:  .::.|.:||:|
  Fly   435 DSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSVCEKTTIPMTYNKEMFLIASNSGIYL 499

Mouse   502  501
              Fly   500  499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4a14	NP_031848.1	p450	52..501	CDD:278495	105/487 (22%)
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	105/487 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900