Protein Alignment Cyp4a14 and Cyp6a19

DIOPT Version :10

• Sequence 1: NP_031848.1
• Gene: Cyp4a14 / 13119
• MGIID: 1096550
• Length: 507
• Species: Mus musculus
• Sequence 2: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 448
• Identity: 119/448 - (26%)
• Similarity: 197/448 - (43%)
• Gaps: 64/448 - (14%)

Mouse    94 VLLYDPDYVKVVLGRSDPK--ASGIY--QFFAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKP 154
            :::.|.|:||.||.|...|  ..|:|  :...| :...|..:.|:||...|:.||..|....:|.
  Fly    82 IVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDP-LTNNLATIEGQKWKNLRQKLTHTFTSAKMKS 145

Mouse   155 Y---VKIMADSVNIMLDKWEKLDGQDHPLEIFHCVSLMTLDTVMKCAFSYQGSVQLDENSKLYTK 216
            .   |..:.|.:..::|  ||:......||:...||..|.|.:..|||..:.:...|..::....
  Fly   146 MFSTVLNVGDEMIRVVD--EKISSSSQTLEVTDIVSRFTSDVIGICAFGLKCNSLRDPKAEFVQM 208

Mouse   217 AVEDLN--------NLTFFRLRNAFYKYNIIYNMSSDGRLSHHACQIAHEHTDGVIKMRKSQLQN 273
            ....|.        :|..|.:.....|....:.:.|                  |.|.....:|:
  Fly   209 GYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLPS------------------VQKFYMKIVQD 255

Mouse   274 EEELQKARKKRHLDFLDILL-----FARMEDRNSLSDEDLRAEVDTFMFEGHDTTASGISWIFYA 333
            ..:.:..||....||:|.|:     :.:.:..|.|:..::.|:...|...|.:..::.:.:..|.
  Fly   256 TIDYRMKRKVTRNDFMDTLIDMKQQYDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYE 320

Mouse   334 LATHPEHQQRCREEVQSILG--DGTSVTWDHLGQMPYTTMCIKEALRLYPPVISVSRELSSPVTF 396
            ||.:.:.|.:.|.|:.|:|.  :| .:.:|.:..:.|....|.|:||.:|.|..::|..:.|..
  Fly   321 LACNQDVQDKLRAEIDSVLERYNG-KLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQ- 383

Mouse   397 PDGRSIPK-----GITATISIYGLHHNPRFWPNPKVFDPSRFAPD--SSHHSHAYLPFSGGSRNC 454
               .|.||     |....:|..|:||:|.|:|.|:.|.|.||..:  ....:.|:|||..|.|||
  Fly   384 ---HSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNC 445

Mouse   455 IGKQFAMNELKVAVALTL--LRFELLPDPTRIPVP----IARLVLKSKNGIHLCLKKL 506
            ||.:|...::.:.:||.:  .||||.|   :.|||    |..|:|.|:.||||.:.|:
  Fly   446 IGLRFGRMQVIIGLALLIHNFRFELHP---KTPVPMKYTINNLLLGSEGGIHLNITKV 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4a14	NP_031848.1	CYP4B-like	69..502	CDD:410771	117/442 (26%)
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	115/440 (26%)