Protein Alignment Cyp4a14 and Cyp4g1

DIOPT Version :10

• Sequence 1: NP_031848.1
• Gene: Cyp4a14 / 13119
• MGIID: 1096550
• Length: 507
• Species: Mus musculus
• Sequence 2: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Alignment Length: 540
• Identity: 148/540 - (27%)
• Similarity: 249/540 - (46%)
• Gaps: 60/540 - (11%)

Mouse    15 ISGFFQWAFLLSLFLVLFKAVQFYLRRQWLLKTLQHFPCMPSHWLWGH-H----LKDKELQQI-L 73
            :.||......|...||.....:::.|.....:.:.:.|..|...:.|. |    |.:.|:..: |
  Fly    21 VLGFSPMLTTLVGTLVAMALYEYWRRNSREYRMVANIPSPPELPILGQAHVAAGLSNAEILAVGL 85

Mouse    74 IWVEKFPSACLQCLSGSNIRVLLYDPDYVKVVL-GRSDPKASGIYQFFAPWIGYGLLLLNGKKWF 137
            .::.|: ...::...|:.:.|.|.:|..::::| |......:..|::|.||.|.|||:.||..|.
  Fly    86 GYLNKY-GETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKPWFGDGLLISNGHHWR 149

Mouse   138 QHRRMLTPAFHYDILKPYVKIMADS-----VNIMLDKWEKLDGQDHPLEIFHCVSLMTLDTVMKC 197
            .||:|:.|.||..|||.:|....|.     ..:.|:..:..|..|:       :|..|:|.::..
  Fly   150 HHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLEAGKSFDVHDY-------MSQTTVDILLST 207

Mouse   198 AFSYQGSVQLDENSKL--YTKAVEDLNNLTFFRLRNAFYKYNIIYNMSSDGRLSHHACQIAHEHT 260
            |   .|..:|.|.:|.  |.:||.|:.::...|.....|:.:.||..:...........|....|
  Fly   208 A---MGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYKFTKLREKGDRMMNIILGMT 269

Mouse   261 DGVIKMRKSQLQNE-----EELQ-------KARK-----------------KRHLDFLDILLFAR 296
            ..|:|.||...|.|     ||:.       .::|                 ||.|..||.::...
  Fly   270 SKVVKDRKENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRLALLDAMVEMA 334

Mouse   297 MEDRNSLSDEDLRAEVDTFMFEGHDTTASGISWIFYALATHPEHQQRCREEVQSILGDG--TSVT 359
            .......:::|:..||:|.||||||||::|.|:....:..|.:.|.:...|.::|.||.  ...|
  Fly   335 KNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNMLRDCT 399

Mouse   360 WDHLGQMPYTTMCIKEALRLYPPVISVSRELSSPVTFPDG-RSIPKGITATISIYGLHHNPRFWP 423
            :....:|.|....|.|.|||||||..::|.|...:....| .::|||.|..:..|.:|..|..:|
  Fly   400 FADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDIYP 464

Mouse   424 NPKVFDPSRFAPD--SSHHSHAYLPFSGGSRNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPV 486
            ||..|||..|.|:  ::.|.::::|||.|.|:|:|:::||.:|||.::..:..:.:....|....
  Fly   465 NPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVHSTDTEADF 529

Mouse   487 PI-ARLVLKSKNGIHLCLKK 505
            .: |.::||.:||.::.|:|
  Fly   530 KLQADIILKLENGFNVSLEK 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4a14	NP_031848.1	CYP4B-like	69..502	CDD:410771	134/476 (28%)
Cyp4g1	NP_525031.1	CYP4	92..545	CDD:410721	132/462 (29%)