Protein Alignment Cyp4a12b and Cyp6a17

DIOPT Version :9

• Sequence 1: NP_758510.2
• Gene: Cyp4a12b / 13118
• MGIID: 3611747
• Length: 508
• Species: Mus musculus
• Sequence 2: NP_001286433.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 563
• Identity: 133/563 - (23%)
• Similarity: 232/563 - (41%)
• Gaps: 146/563 - (25%)

Mouse    21 VASVLSLLLLLFKTAQLYLHRQWLLSSTQQFPSPPSHWLFGHKILKD--------QDLQDILTRI 77
            :..:||||:...:....|..|:.:       |....|.|||:  :||        :..:|...:.
  Fly     7 IVVILSLLVFAARRRHGYWQRRGI-------PHDEVHPLFGN--IKDWPNKRHIAEIFRDYYFKY 62

Mouse    78 KN--FPSACPQWLWGSKVRIQVYDPDYMKLILGR---------------SDPKAHGSYRFLAPWI 125
            ||  :|.| ..:.:.::..: |.|.:.:|.:|.:               .||            :
  Fly    63 KNSDYPFA-GFFFFFTRTAV-VTDMELLKRVLIKDFNHFENRGVFYNEIDDP------------L 113

Mouse   126 GRGLLLLDGQTWFQHRRMLTPAFHYDILKPYTEIMADSVHVMLDK---WEQIVGQDSTLEIFQHI 187
            ...|..::||.|...|..|||.|....:|....|:. .|...:||   .:....:...||:...:
  Fly   114 SATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIVV-KVGEEMDKVFRSKTAADRGQVLEVVDLV 177

Mouse   188 TLMTLDTIMKCAF-----------------------SHE----------GSVQLDR--KYKSYIQ 217
            ...|.|.|..|||                       .|.          |..:|.|  :.|..||
  Fly   178 ARYTADVIGNCAFGLNCNSLYDPKAEFVSIGKRAITEHRYGNMLDIFLFGFPKLSRRLRLKLNIQ 242

Mouse   218 AVEDLNNLFFLRVRNIFHQNDIIYRVSSNGCLANSACQLAHDHTDQVIKSRRSQLQDEEELEKLK 282
            ..||    |:.::    .:..|.||:.:
  Fly   243 EAED----FYTKI----VRETIDYRLRT------------------------------------- 262

Mouse   283 KKRRLDFLDIL--LFARMENGKS---LSDKDLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQ 342
            |::|.||:|.|  ::...::|.|   |:..:|.|:...|...|.:|:::.:.:..|.||.|.:.|
  Fly   263 KEKRNDFMDSLIEMYKNEQSGNSEDGLTFNELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQ 327

Mouse   343 QRCRKEIQSLLG-DGASITWNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSPVTFPDGR-SLPK 405
            .:.|:||.::.| .....|:..:.:|.|....:.|.||.||.:..::|...:..:..|.: .:.|
  Fly   328 DKLREEIGNVFGKHNKEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFSPEDPKYFIAK 392

Mouse   406 GIHVMLSFYGLHHNPTVWPNPEVFDPSRFAPG--SSRHSHSFLPFSGGARNCIGKQFAMNELKVA 468
            |..|::...|:|::|.::|.||:|.|.||...  ::|.|.::|||..|.|||||.:|.|.:..|.
  Fly   393 GTIVVIPALGIHYDPDIYPEPEIFKPERFTDEEIAARPSCTWLPFGEGPRNCIGLRFGMMQTCVG 457

Mouse   469 VALTL--LRFELLPDPTRVP--IPIPRIVLKSKNGIHLHLKKL 507
            :|..:  .:|.:.|: |::|  |.:..|::.::|||||.::||
  Fly   458 LAYLIRGYKFSVSPE-TQIPMKIVVKNILISAENGIHLKVEKL 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4a12b	NP_758510.2	CYP4B-like	70..503	CDD:410771	117/500 (23%)
Cyp6a17	NP_001286433.1	p450	36..478	CDD:278495	117/504 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900