Protein Alignment Cyp4a12b and Cyp6a19

DIOPT Version :10

• Sequence 1: NP_758510.2
• Gene: Cyp4a12b / 13118
• MGIID: 3611747
• Length: 508
• Species: Mus musculus
• Sequence 2: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 457
• Identity: 126/457 - (27%)
• Similarity: 205/457 - (44%)
• Gaps: 67/457 - (14%)

Mouse    87 WLWGSKVRIQVYDPDYMKLILGRSDPKAH--GSYRFLA--PWIGRGLLLLDGQTWFQHRRMLTPA 147
            :|:..|. |.:.|.|::|.:|.|...|.|  |.|....  | :...|..::||.|...|:.||..
  Fly    75 YLYAMKY-IVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDP-LTNNLATIEGQKWKNLRQKLTHT 137

Mouse   148 FHYDILKP-YTEIM--ADSVHVMLDKWEQIVGQDSTLEIFQHITLMTLDTIMKCAFSHEGSVQLD 209
            |....:|. ::.::  .|.:..::|  |:|.....|||:...::..|.|.|..|||..:.:...|
  Fly   138 FTSAKMKSMFSTVLNVGDEMIRVVD--EKISSSSQTLEVTDIVSRFTSDVIGICAFGLKCNSLRD 200

Mouse   210 RKYKSYIQAVEDLNNLFFLRVRN--------IFHQNDIIYRVSSNGCLANSACQLAHDHTDQVIK 266
            .| ..::|.     ....||.|.        ||....:..::.....|.:            |.|
  Fly   201 PK-AEFVQM-----GYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLPS------------VQK 247

Mouse   267 SRRSQLQDEEELEKLKKKRRLDFLDILLFARM-------ENGKSLSDKDLRAEVDTFMFEGHDTT 324
            .....:||..:....:|..|.||:|.|:..:.       |||  |:..::.|:...|...|.:..
  Fly   248 FYMKIVQDTIDYRMKRKVTRNDFMDTLIDMKQQYDKGDKENG--LAFNEVAAQAFVFFLAGFEAG 310

Mouse   325 ASGISWIFYALATNPEHQQRCRKEIQSLLGD-GASITWNDLDKMPYTTMCIKEALRIYPPVPSVS 388
            ::.:.:..|.||.|.:.|.:.|.||.|:|.. ...:.::.:..:.|....|.|:||.:|.|..::
  Fly   311 STTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLA 375

Mouse   389 RELSSPVTFPDGRSLPK-----GIHVMLSFYGLHHNPTVWPNPEVFDPSRF--APGSSRHSHSFL 446
            |..:.|..    .|.||     |..|::|..|:||:|..:|.||.|.|.||  .....|.:.:||
  Fly   376 RIATKPYQ----HSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRPTCAFL 436

Mouse   447 PFSGGARNCIGKQFAMNELKVAVALTL--LRFELLPDPTRVPIP----IPRIVLKSKNGIHLHLK 505
            ||..|.|||||.:|...::.:.:||.:  .||||.|   :.|:|    |..::|.|:.||||::.
  Fly   437 PFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHP---KTPVPMKYTINNLLLGSEGGIHLNIT 498

Mouse   506 KL 507
            |:
  Fly   499 KV 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4a12b	NP_758510.2	CYP4B-like	70..503	CDD:410771	124/451 (27%)
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	122/449 (27%)