Protein Alignment Cyp4a12b and Cyp4p2

DIOPT Version :9

• Sequence 1: NP_758510.2
• Gene: Cyp4a12b / 13118
• MGIID: 3611747
• Length: 508
• Species: Mus musculus
• Sequence 2: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Alignment Length: 519
• Identity: 146/519 - (28%)
• Similarity: 241/519 - (46%)
• Gaps: 92/519 - (17%)

Mouse    57 HWLFGHKILKDQDLQDILTRI------KNFPSACPQWLWGSKVRIQVYD---------------- 99
            ||::  |:.||.::.....|.      |...|..|. :.|..|....:|
  Fly    17 HWIY--KVNKDYNILAFFARRVQTKDGKPLDSLVPM-IKGRTVFANCFDLLGKDTDQVFTHLRQL 78

Mouse   100 -----PDYMKLILGRSD---PKAHGS---------------YRFLAPWIGRGLLLLDGQTWFQHR 141
                 ..|::..:|.|:   ..||.:               |.||.|::..|:|....:.|...|
  Fly    79 AKNSGDSYLQYSMGFSNFNVIDAHNAANILNHPNLITKGVIYNFLHPFLRTGVLTATEKKWHTRR 143

Mouse   142 RMLTPAFHYDILKPYTEI-MADSVHVMLDKWEQIVGQDS-TLEIFQHITLMTLDTIMKCAFSHEG 204
            .|||..||.|||..:.|| :|:|:..:    .|..||:. .:.:...|:..||::|.:.|.
  Fly   144 SMLTRTFHLDILNQFQEIFIAESLKFV----SQFQGQNEVVVSLKDRISRFTLNSICETAM---- 200

Mouse   205 SVQLDR------KYKSYIQAV-EDLNNLFFLRVRNIFHQNDIIYRVSSNGCLANSACQLAHDHTD 262
            .::||.      :|::....: |.|..    |:.|..:.:|.:|.:.: |...|:|.::.|:.:.
  Fly   201 GIKLDEMAEKGDRYRANFHIIDEGLTR----RIVNPLYWDDCVYNMFT-GHKYNAALKVVHEFSR 260

Mouse   263 QVIKSRRSQLQDEEELEKLK------------KKRRLDFLDILLFARMENGKSLSDKDLRAEVDT 315
            ::|..||..|  |||||..:            :|:|...||.|:.|  |....:.|..:..||||
  Fly   261 EIIAKRRVLL--EEELENRRATQTADDDICVIRKKRFAMLDTLICA--EKDGLIDDIGISEEVDT 321

Mouse   316 FMFEGHDTTASGISWIFYALATNPEHQQRCRKEIQS-LLGDGASITWNDLDKMPYTTMCIKEALR 379
            .|.||:|||:.|:.:....::.....|:.|.:|||. :|.|.:::..:.|.|:.|....|||.:|
  Fly   322 LMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEHILDDLSNLNLSQLSKLNYLGYFIKETMR 386

Mouse   380 IYPPVPSVSRELSSPVTFPDGRSLPKGIHVMLSFYGLHHNPTVWPNPEVFDPSRFAPGS--SRHS 442
            :||.:|.:.|:........:|..|||...:.:..:.:|.||..|.:||.|.|.||.|.:  .||.
  Fly   387 LYPSIPIMGRQTLQETELENGLILPKRSQINIHVFDIHRNPKYWESPEEFRPERFLPQNCLKRHP 451

Mouse   443 HSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLP--DPTRVPIPIPRIVLKSKNGIHLHL 504
            ::::|||.|.|||||:::||.|:|..:.:.|..|::||  ||..:...: .|.|:.||.|.:.|
  Fly   452 YAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKILPVIDPKSIVFQV-GITLRFKNKIKVKL 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4a12b	NP_758510.2	CYP4B-like	70..503	CDD:410771	140/503 (28%)
Cyp4p2	NP_610472.1	p450	63..514	CDD:299894	133/468 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845071
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850