Protein Alignment Cyp4a12b and Cyp4d21

DIOPT Version :9

• Sequence 1: NP_758510.2
• Gene: Cyp4a12b / 13118
• MGIID: 3611747
• Length: 508
• Species: Mus musculus
• Sequence 2: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Alignment Length: 537
• Identity: 149/537 - (27%)
• Similarity: 256/537 - (47%)
• Gaps: 90/537 - (16%)

Mouse    24 VLSLLLLLFKTAQLYLHRQWLLSSTQQ------FPSPPSHWLFGHKILKDQDLQDILTRIKNFPS 82
            :|.:.:|:.........:||.:::.::      |..|          :....||.:..|.:||..
  Fly     4 LLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIP----------IVGNGLQALTLRPENFIQ 58

Mouse    83 ACPQWL--WGSKVRI------QVYDPD--YMKLILGRSD--PKAHGSYRFLAPWIGRGLLLLDGQ 135
            ....:.  :|...|:      .:|..|  |.:.||..|.  .||| .||||..::|.||||..|.
  Fly    59 RFGDYFNKYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAH-LYRFLRDFLGDGLLLSTGN 122

Mouse   136 TWFQHRRMLTPAFHYDILKPYTEIMADSVHVMLDKWEQIVGQDSTLEIFQHITLMTLDTIMKCAF 200
            .|...|::|.||||:..|:.:.|||..:..:|::|.:......:.:::|:.::|..||...:.|.
  Fly   123 KWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETAM 187

Mouse   201 SHEGSVQLDRKYKSYIQAVEDL---------------NNLFFLRVRNIFH--QNDIIYRVSSNGC 248
            ..:.:.|.:..: .|.:|::.:               |.||.|....::.  |.||
  Fly   188 GVQVNAQNEPNF-PYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDI--------- 242

Mouse   249 LANSACQLAHDHTDQVIKSRRSQLQ--------------DEEELEKLKKKRRLDFLDILLFARME 299
                  .:..|.||:||:.||:.|:              |::    :..|.::..|||||.|.::
  Fly   243 ------AIMQDFTDKVIRERRAILERARADGTYKPLIMGDDD----IGGKAKMTLLDILLQATID 297

Mouse   300 NGKSLSDKDLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQRCRKEIQSLLG--DGASITWN 362
            | |.|||.|:|.|||.|:|.|.|||.||:|...:|::.:|:.|:...:|:.|:||  ..||:|..
  Fly   298 N-KPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQT 361

Mouse   363 DLDKMPYTTMCIKEALRIYPPVPSVSRELSSPVTFPDGR-SLPKGIHVMLSFYGLHHNPTVWPNP 426
            .|.::.|....|||.:|::||||.:.|.:  |.....|. ::|....::|..|.::.:|..:|:|
  Fly   362 KLLELKYLDCVIKETMRLHPPVPILGRYI--PEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDP 424

Mouse   427 EVFDPSRF---APGSSRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRVPIP 488
            .||.|.|:   ...|:....:::|||.|.:||||::||..::|..::..:..:||||....:...
  Fly   425 LVFKPERWMDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLPLGADLKAT 489

Mouse   489 IPRIVLKSKNGIHLHLK 505
            . ..:|.|..|.::.||
  Fly   490 Y-TFILSSSTGNNVGLK 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4a12b	NP_758510.2	CYP4B-like	70..503	CDD:410771	141/481 (29%)
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	139/480 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845024
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D214327at33208
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750