Protein Alignment Cyp4a10 and Cyp4c3

DIOPT Version :10

• Sequence 1: NP_034141.3
• Gene: Cyp4a10 / 13117
• MGIID: 88611
• Length: 509
• Species: Mus musculus
• Sequence 2: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 533
• Identity: 163/533 - (30%)
• Similarity: 276/533 - (51%)
• Gaps: 74/533 - (13%)

Mouse    15 LSGFLQV-ASVLGLLLLLVKAVQFYLHRQWLLKAFQQFPSPPFHWFFGH---------EKFK--- 66
            :||:..: ..:||.:|:.:  |.:...|..|:|..::.|.|....|.|:         |.|.
  Fly    23 ISGYSPITVFLLGSILIFL--VVYNKRRSRLVKYIEKIPGPAAMPFLGNAIEMNVDHDELFNRVI 85

Mouse    67 GDQELQEIVSCIENFPSAFPRWFWGSKAYLT-----------VYDPDYMKVILGRSDPKANGA-- 118
            |.|:|                  ||::..:.           :::|:.::.|| .|....|.:
  Fly    86 GMQKL------------------WGTRIGINRVWQGTAPRVLLFEPETVEPIL-NSQKFVNKSHD 131

Mouse   119 YRLLAPWIGYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLADQ--DSS 181
            |..|.||:|.|||....:.|...|::||||||:.||..::....:...::..|   ||.:  ..:
  Fly   132 YDYLHPWLGEGLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARK---LAVEVGSEA 193

Mouse   182 IEIFQHISLMTLDTVMKCAFSHKGSVQVDGNYRT-YLQAIGDLNNLFHSRVRNIFHQNDTIYKLS 245
            ..:|.:::|.|||.|.:.|...:  :....|..: |::|:..:.::..||...|:.|:|.|:.|:
  Fly   194 FNLFPYVTLCTLDIVCETAMGRR--IYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLT 256

Mouse   246 SNGRLAKQACQLAHDHTDGVIKLRKDQ---LQDEGE---------LEKIKKKRRLDFLDILLFAR 298
            :..:|.:......|..::.||:.||.:   ||:...         .:.:.||:||.|||:|:.|.
  Fly   257 AEYKLHQSYINTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDAS 321

Mouse   299 MENGDSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPDHQQRCREEVQSLLGDG--SSIT 361
            .| |..:|::|:|.|||||||||||||::.:||..:.|..||::|:|..||:.|:.||.  :..|
  Fly   322 KE-GTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPAT 385

Mouse   362 WDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVWPN 426
            ..:|..:.|...|||::|||:|.||.:.|.:...|.. .|:.:|.|.|..:..|.||.||:|:|.
  Fly   386 MKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNI-GGKIVPAGTQAIIMTYALHRNPRVFPK 449

Mouse   427 PEVFDPSRFAPD--SPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLPDPTRVPMP 489
            ||.|:|..|.|:  :.||..:::|||.|.|||||::||:.|.|.:::..|.::::.....|..:.
  Fly   450 PEQFNPDNFLPENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRREDLT 514

Mouse   490 -LARLVLKSKNGI 501
             |..|:|:.|:|:
  Fly   515 LLGELILRPKDGL 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4a10	NP_034141.3	CYP4B-like	71..504	CDD:410771	146/464 (31%)
Cyp4c3	NP_524598.1	CYP4V-like	96..529	CDD:410753	143/440 (33%)