Protein Alignment Cyp4a10 and Cyp6a23

DIOPT Version :9

• Sequence 1: NP_034141.3
• Gene: Cyp4a10 / 13117
• MGIID: 88611
• Length: 509
• Species: Mus musculus
• Sequence 2: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Alignment Length: 559
• Identity: 126/559 - (22%)
• Similarity: 229/559 - (40%)
• Gaps: 136/559 - (24%)

Mouse    24 VLGLLLLLVKAVQFYLHRQ---WLLKAFQQFPSPPFHWFFGHEKFKGDQELQEIVSCIENFPSAF 85
            :|.|:.|||..:.|...|:   |..:.   .|....|..:|:  .|...:.:.|.....::.:.:
  Fly     4 LLTLIALLVSLLLFMARRRHGYWQRRG---IPHDVPHPIYGN--MKDWPKKRHIAMIFRDYYTKY 63

Mouse    86 PR---------WFWGSKAYLTVYDPDYMKVILGR---------------SDPKANGAYRLLAPWI 126
            .|         :|:...|.:|  |.:.:|.:|.:               .||            :
  Fly    64 KRSVYPFAGFYFFFTRSAVIT--DLELVKRVLIKDFNHFENRGIFYNEIDDP------------L 114

Mouse   127 GYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERL------ADQDSSIEIF 185
            ...|..:.||.|...|..|||.|    ....:|||...|..:.::.|::      ..:...:||.
  Fly   115 SATLFSIEGQKWRHLRHKLTPTF----TSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQVLEIV 175

Mouse   186 QHISLMTLDTVMKCAFS-HKGSVQ--------------VDGNYRTYLQ----------------- 218
            ..::..|.|.:..|||. :..|:|              ::..|...|.
  Fly   176 DLVARYTADVIGNCAFGLNCNSLQNPNAEFVTIGKRAIIERRYGGLLDFLIFGFPKLSRRLRLKL 240

Mouse   219 AIGDLNNLFHSRVRNIFHQNDTI-YKLSSNGRLAKQACQLAHDHTDGVIKL-RKDQLQDEGELEK 281
            .:.|:.:.:.|.|||      || |:|.:|        :..||..|.:|:: .|:|   .|..|
  Fly   241 NVQDVEDFYTSIVRN------TIDYRLRTN--------EKRHDFMDSLIEMYEKEQ---AGNTE- 287

Mouse   282 IKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPDHQQRC 346
                                 |.:|..::.|:...|...|.:|:::.:.:..|.||...|.|.:.
  Fly   288 ---------------------DGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQL 331

Mouse   347 REEVQSLLG-DGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGR-SLPKGVQ 409
            |.|:.::|. ..:..|::.:.::.|....:.|.||.||.:..:.|...|..:..|.: .:.||..
  Fly   332 RAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTT 396

Mouse   410 VTLSIYGLHHNPKVWPNPEVFDPSRFAPD--SPRHSHSFLPFSGGARNCIGKQFAMSELKVIVAL 472
            |.:...|:|::|:::|.||.|.|.||..:  :.|.|.::|||..|.|||||.:|.:.:..|.:|.
  Fly   397 VVIPALGIHYDPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAY 461

Mouse   473 TLLRFEL-LPDPTRVPMP--LARLVLKSKNGIYLHLKKL 508
            .:..::. :...|::||.  :..::|.::|||:|.::||
  Fly   462 LIRGYKFSVSTETQIPMKFVVKSILLSAENGIHLKVEKL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4a10	NP_034141.3	p450	52..503	CDD:278495	115/521 (22%)
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	114/517 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900