Protein Alignment Cyp4a10 and Cyp4d21

DIOPT Version :9

• Sequence 1: NP_034141.3
• Gene: Cyp4a10 / 13117
• MGIID: 88611
• Length: 509
• Species: Mus musculus
• Sequence 2: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Alignment Length: 495
• Identity: 148/495 - (29%)
• Similarity: 256/495 - (51%)
• Gaps: 54/495 - (10%)

Mouse    24 VLGLLLLLVKAVQFYLHRQWLLKAFQQ------FPSPPFHWFFGHEKFKGDQELQEIVSCIENFP 82
            :||:.:|::..|.....:||.:..|::      |..|    ..|:       .||.:....|||.
  Fly     4 LLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIP----IVGN-------GLQALTLRPENFI 57

Mouse    83 SAFPRWF--WGSKAYL------TVYDPD--YMKVILGRSD--PKANGAYRLLAPWIGYGLLLLNG 135
            ..|..:|  :|....|      .:|..|  |.:.||..|.  .||: .||.|..::|.||||..|
  Fly    58 QRFGDYFNKYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAH-LYRFLRDFLGDGLLLSTG 121

Mouse   136 QPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLADQDSSIEIFQHISLMTLDTVMKCA 200
            ..|...|::|.||||:..|:.:|:.|..:..:|::|.:..||..:.:::|:.:||..||...:.|
  Fly   122 NKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETA 186

Mouse   201 FSHKGSVQVDGNYRTYLQAIGDLNNLFHSRVRNIFHQNDTIYKLSS---NGRLAKQACQLAHDHT 262
            ...:.:.|.:.|: .|.:|:..:..:...|:.::..:.:.::.|::   ..||.|... :..|.|
  Fly   187 MGVQVNAQNEPNF-PYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIA-IMQDFT 249

Mouse   263 DGVIKLRK---DQLQDEGEL-------EKIKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTF 317
            |.||:.|:   ::.:.:|..       :.|..|.::..|||||.|.::| ..:||.|:|.|||.|
  Fly   250 DKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDN-KPLSDVDIREEVDVF 313

Mouse   318 MFEGHDTTASGVSWIFYALATHPDHQQRCREEVQSLLG--DGSSITWDHLDQIPYTTMCIKEALR 380
            :|.|.|||.||||...:|::.||..|:...||:.|:||  ..:|:|...|.::.|....|||.:|
  Fly   314 IFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMR 378

Mouse   381 LYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHSH- 444
            |:||||.:.|.:...:...: .::|....:.|..|.::.:|:.:|:|.||.|.|:. |....|:
  Fly   379 LHPPVPILGRYIPEDLKIGE-ITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWM-DMKTTSNT 441

Mouse   445 ---SFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLP 481
               :::|||.|.:||||::||..::|.:::..:..:||||
  Fly   442 PPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4a10	NP_034141.3	p450	52..503	CDD:278495	140/461 (30%)
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	141/464 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845124
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740