Protein Alignment Cyp46a1 and Cyp4p1

DIOPT Version :9

• Sequence 1: NP_034140.1
• Gene: Cyp46a1 / 13116
• MGIID: 1341877
• Length: 500
• Species: Mus musculus
• Sequence 2: NP_524828.1
• Gene: Cyp4p1 / 45524
• FlyBaseID: FBgn0015037
• Length: 513
• Species: Drosophila melanogaster
• Alignment Length: 532
• Identity: 114/532 - (21%)
• Similarity: 223/532 - (41%)
• Gaps: 93/532 - (17%)

Mouse    12 VLLAFGLCCTFVHRARSRYEHIPGPPRPSFLLGHLPYFWK----KD------------------- 53
            ::||......::|||...| ||            |.:|.|    ||
  Fly     6 LILALSALLYWLHRANKDY-HI------------LSFFTKRIRLKDGTPVEIIAPIAKGKTIFGN 57

Mouse    54 --EDCGRVLQDVF---LDWAKKYGPVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQ 113
              :..||....||   .:.||:.|......||.|....:...:|.:..|     |..:.:.:.|.
  Fly    58 TLDLYGRDHAGVFNYSRERAKEMGTSYIEYVFGKAIYNIIDADSAENVL-----NHPNLITKGLV 117

Mouse   114 TVFGERLFGQGLVSECDYGRWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPV 178
            ..|.......||::... .:|:.:||::...|..:.|....|.|..::::.  :|:.:...:..:
  Fly   118 YNFLHPFLRTGLLTSTG-KKWHARRKMLTPTFHFNILNQFQEIFKTESQKF--LLQFEGQDEVTI 179

Mouse   179 SMQDMLTCATIDILAKAAFGMETSMLLGAQK------PLSQAVKVMLEGISAS---RNTLAKFMP 234
            ::.|::...|::.:.:.|.|::...:  |:|      ..||..:..:..:|..   .:.|.:...
  Fly   180 TLHDVIPRFTLNSICETAMGVKLDEM--AEKGDRYRENFSQIEECFIRRLSNPLLWGDKLFEMFA 242

Mouse   235 GKRKQLREIRESIRLLRQVGKDWVQRRREALKRGEDMPAD--------------ILTQILKAEEG 285
            .|     :...::.::.:...:.:.:||:.||...|..:.              :|..::.||:.
  Fly   243 AK-----DFASALDVVHRFSSEIIAKRRDLLKDELDKSSSTADDDGFVSKKRFAMLDTLIYAEKD 302

Mouse   286 AQDDEV-LLDNFVTFFIAGHETSANHLAFTVMELSRQPE----IVARLQAEVDEVVGSKRHLDYE 345
            ...|.: :.:...|....|::|::..|.|.:|.:|..|:    ....:|..:|:.:.   :||..
  Fly   303 GLIDHIGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQELCYQEIQEHIDDDLS---NLDVG 364

Mouse   346 DLGRLQYLSQVLKESLRLYP--PAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDP 408
            .|.:|:||...:||:.||:|  |..|. ..::|..|.:|:.:|....:....:.:.|...|::.|
  Fly   365 QLNKLKYLEYFMKETTRLFPSVPIMGR-EAVQETELANGLILPKGAQITIHVFDIHRNAKYWDSP 428

Mouse   409 LTFNPDRFGPGAPKPRFT--YFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIE-FRLVPGQRFGL 470
            ..|.|:||.|...:.|.|  |.|||.|.|:|||:::|..|:|.:|..||::.: .:.:..|:...
  Fly   429 EEFRPERFLPENVQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQFKVLKAIDPQKIVF 493

Mouse   471 QEQATLKPLDPV 482
            ....||:..|.:
  Fly   494 HTGITLRTQDKI 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp46a1	NP_034140.1	p450	34..466	CDD:278495	102/492 (21%)
Cyp4p1	NP_524828.1	p450	54..509	CDD:278495	101/471 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000