Protein Alignment Cyp46a1 and Cyp4e1

DIOPT Version :9

• Sequence 1: NP_034140.1
• Gene: Cyp46a1 / 13116
• MGIID: 1341877
• Length: 500
• Species: Mus musculus
• Sequence 2: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Alignment Length: 469
• Identity: 123/469 - (26%)
• Similarity: 209/469 - (44%)
• Gaps: 70/469 - (14%)

Mouse    64 FLDWAKKYG-PVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVS 127
            |..|..:|| ...|..:.|.::::||:|:.::..|.|......|.:|.....     ..|.||::
  Fly    59 FFGWWHEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHP-----WLGLGLLT 118

Mouse   128 ECDYGRWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTCATIDIL 192
            ... .:|:|.||::..||..:.|....|..||.:.:.::.|:..|||......|:.....|:|::
  Fly   119 STG-SKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVI 182

Mouse   193 AKAAFGMETSMLLGAQKPLSQAVKVMLEGISASRNTLAKFMPGKRK--------QLREIRESIRL 249
            ...|.|:..:.:......:.||.|.:...|.     :..|.|.||.        :..|..::::.
  Fly   183 CDTAMGVSINAMENRSSSVVQAFKDITYTIK-----MRAFSPWKRNKYLFHFAPEYPEYSKTLKT 242

Mouse   250 LRQVGKDWVQRRREALKRGEDMPADILTQILKAEEGAQDDEVLLDNFV----------------- 297
            |:....:.:.:|.|..|.|.::.       :||:|.::.....||..:
  Fly   243 LQDFTNEIIAKRIEVRKSGLEVG-------IKADEFSRKKMAFLDTLLSSKVDGRPLTSQELYEE 300

Mouse   298 --TFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSK---RHLDYEDLGRLQYLSQVL 357
              ||...||:|:.:.:.|.|..|||.|:...:|..|..:|:|:.   |...::::..:::|...:
  Fly   301 VSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFI 365

Mouse   358 KESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGAPK 422
            ||:.||||......|..|::.:|||..||..|.|.....::|..|..|:||..|.|:||....|.
  Fly   366 KEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDREKPG 430

Mouse   423 PRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRLVP------------GQRFGLQ---- 471
            | |.|.|||.|.|:||||:||.:|:|.|::|:::  .|.::|            ....|||
  Fly   431 P-FEYVPFSAGPRNCIGQKFALLEIKTVVSKIIR--NFEVLPALDELVSKDGYISTTLGLQPAEK 492

Mouse   472 --EQATLKPLDPVL 483
              ..|.....||:|
  Fly   493 KSRDAHNHKYDPIL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp46a1	NP_034140.1	p450	34..466	CDD:278495	116/444 (26%)
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	115/430 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810