Protein Alignment Cyp46a1 and Cyp313a1

DIOPT Version :9

• Sequence 1: NP_034140.1
• Gene: Cyp46a1 / 13116
• MGIID: 1341877
• Length: 500
• Species: Mus musculus
• Sequence 2: NP_650368.1
• Gene: Cyp313a1 / 41759
• FlyBaseID: FBgn0038236
• Length: 492
• Species: Drosophila melanogaster
• Alignment Length: 502
• Identity: 106/502 - (21%)
• Similarity: 199/502 - (39%)
• Gaps: 130/502 - (25%)

Mouse     4 GLLLLGSAV--LLAFGLCCTFVHRARSRYEHIPGPPRPSFLLGHLPYFWKKDEDCGRVLQDVFLD 66
            ||.:|||::  ::.:....:|    |::|.:..|....:: :|.:|:...:|.   :|::|:|
  Fly    37 GLPILGSSLENIITYKRKLSF----RTKYLNKYGSTILTW-MGPVPFIVTRDP---KVVEDIF-- 91

Mouse    67 WAKKYGPVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSECDY 131
                                 :||:.         :||...:..|:.:..|..|.|:      ..
  Fly    92 ---------------------SSPDC---------HNKSQHIVNAITSCMGNGLLGK------QD 120

Mouse   132 GRWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKAD-GQTPVSMQDMLTCATIDILAKA 195
            ..|..:||..:.:|.:..|:|....|:.:.:.|:.:|:...| |:             ||::.:.
  Fly   121 PHWLDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKGE-------------IDVVPEM 172

Mouse   196 AFGMETSMLLGAQKPLSQAVK--------VMLEGISA--SRNTLAKFMPGKRKQL---------- 240
               :..|..:.||..:...||        .::|...:  |.:||...||..:.::
  Fly   173 ---LRWSFKIAAQTTMGSEVKHDEHFKNGSLVESFESLISHSTLNILMPLVQNRMISKICGYDKL 234

Mouse   241 -------------REIRESIRLLRQVGKD-----WVQRRREALKRGEDMPADILTQILKAEEGAQ 287
                         ..:.:.:..|.:...|     .:.|..|..::|     ||....:|:|
  Fly   235 RADNFSRIQKMLDNVVNKKVNPLPKTDSDPESNIVINRAMELYRKG-----DITYMDVKSE---- 290

Mouse   288 DDEVLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRH--LDYEDLGRL 350
                    ......||::|||..:...:..|:..||....:..|::.|.....|  :.|.|:.:|
  Fly   291 --------CCIMIAAGYDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDMQKL 347

Mouse   351 QYLSQVLKESLRLYPPAWGTFRLLEEET-LIDGVRVPGNTPL---LFSTYVMGRMDTYFEDPLTF 411
            .||.:|:||:|||.|....|.|..:.:. |.:||.:|....:   :|.|:  ...:.:..|...|
  Fly   348 DYLERVIKETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIGIDMFHTH--RNPEVWGPDADNF 410

Mouse   412 NPDRF--GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQ 456
            |||.|  .....|..:.|.||:.|.|:|||.::|.|..|..:.::|:
  Fly   411 NPDNFLAENMEQKHPYAYIPFARGKRNCIGSKYAMMSSKFALCRILR 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp46a1	NP_034140.1	p450	34..466	CDD:278495	98/470 (21%)
Cyp313a1	NP_650368.1	p450	33..463	CDD:299894	106/502 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010