Protein Alignment Cyp46a1 and Cyp4p2

DIOPT Version :10

• Sequence 1: NP_034140.1
• Gene: Cyp46a1 / 13116
• MGIID: 1341877
• Length: 500
• Species: Mus musculus
• Sequence 2: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Alignment Length: 375
• Identity: 94/375 - (25%)
• Similarity: 169/375 - (45%)
• Gaps: 66/375 - (17%)

Mouse   133 RWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTCATIDILAKAAF 197
            :|:.:|.::...|....|....|.|  .||.|..:.:.:...:..||::|.::..|::.:.:.|.
  Fly   138 KWHTRRSMLTRTFHLDILNQFQEIF--IAESLKFVSQFQGQNEVVVSLKDRISRFTLNSICETAM 200

Mouse   198 GMETSMLLGAQK---------------------PL---------------SQAVKVMLEGISASR 226
            |::...:  |:|                     ||               :.|:||:.|   .||
  Fly   201 GIKLDEM--AEKGDRYRANFHIIDEGLTRRIVNPLYWDDCVYNMFTGHKYNAALKVVHE---FSR 260

Mouse   227 NTLAKFMPGKRKQLREIRESIRLLRQVGKD--WVQRRREALKRGEDMPADILTQILKAEEGAQDD 289
            ..:||    :|..|.|..|:.|..:....|  .::::|.|:         :.|.|...::|..||
  Fly   261 EIIAK----RRVLLEEELENRRATQTADDDICVIRKKRFAM---------LDTLICAEKDGLIDD 312

Mouse   290 EVLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDE-VVGSKRHLDYEDLGRLQYL 353
            ..:.:...|....|::|::..|.|.:|.:|...........|:.| ::....:|:...|.:|.||
  Fly   313 IGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEHILDDLSNLNLSQLSKLNYL 377

Mouse   354 SQVLKESLRLYP--PAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRF 416
            ...:||::||||  |..|. :.|:|..|.:|:.:|..:.:....:.:.|...|:|.|..|.|:||
  Fly   378 GYFIKETMRLYPSIPIMGR-QTLQETELENGLILPKRSQINIHVFDIHRNPKYWESPEEFRPERF 441

Mouse   417 GPGAPKPR--FTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRLVP 464
            .|.....|  :.|.|||.|.|:||||::|..|:|.:|..:|:  .|:::|
  Fly   442 LPQNCLKRHPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILK--HFKILP 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp46a1	NP_034140.1	CYP46A1-like	61..484	CDD:410706	94/375 (25%)
Cyp4p2	NP_610472.1	CYP4	83..512	CDD:410721	94/375 (25%)