Protein Alignment Cyp46a1 and Cyp4ac2

DIOPT Version :10

• Sequence 1: NP_034140.1
• Gene: Cyp46a1 / 13116
• MGIID: 1341877
• Length: 500
• Species: Mus musculus
• Sequence 2: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Alignment Length: 410
• Identity: 103/410 - (25%)
• Similarity: 194/410 - (47%)
• Gaps: 46/410 - (11%)

Mouse    80 FYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSECDYGRWYKQRKVMDLA 144
            |:.....:...|..::.|.|:|....:.:|..|:...||     ||:...|. :|:.:||.:..|
  Fly    92 FHAPMYNIVRAEEAEEILQSSKLITKNMIYELLKPFLGE-----GLLISTDQ-KWHSRRKALTPA 150

Mouse   145 FSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTCATIDILAKAAFGMETSMLLGAQK 209
            |....|.|.:..|.|:..:||::|....:.:  :.:..::...|::.:.:.|.|::..
  Fly   151 FHFKVLQSFLIIFKEECNKLVKVLHQSVNME--LELNQVIPQFTLNNVCETALGVKLD------- 206

Mouse   210 PLSQAVKV-----MLEGISASR-------NTLAKFMPGK-RKQLREIRESIRLLRQVGKDWVQRR 261
            .||:.::.     .:|.:...|       |.:..|:.|. |||:    .::::..:...:.:::|
  Fly   207 DLSEGIRYRQSIHAIEEVMQQRLCNPFFYNIVYFFLFGDYRKQV----NNLKIAHEFSSNIIEKR 267

Mouse   262 REALKR---------GEDMPADILTQILKAE-EGAQDDEVLLDNFVTFFIAGHETSANHLAFTVM 316
            |...|.         |:.....:|..:|.|| :|..|.:.:.|...||...|::|::..|.||::
  Fly   268 RSLFKSNQLGQEDEFGKKQRYAMLDTLLAAEADGQIDHQGICDEVNTFMFEGYDTTSTCLIFTLL 332

Mouse   317 ELSRQPEIVARLQAEVDEVVGSKRHLDYEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLID 381
            .|:...::..:...|:..:......:.......|.|:..|:||||||:|......|...||.:::
  Fly   333 MLALHEDVQKKCYEEIKYLPDDSDDISVFQFNELVYMECVIKESLRLFPSVPFIGRRCVEEGVVN 397

Mouse   382 GVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGAPKPR--FTYFPFSLGHRSCIGQQFAQ 444
            |:.:|.||.:....|.:.|...:|.:|..|.||||.|.....|  |.:.|||.|.|:||||:||.
  Fly   398 GLIMPKNTQINIHLYEIMRDARHFSNPKMFQPDRFFPENTVNRHPFAFVPFSAGQRNCIGQKFAI 462

Mouse   445 MEVKVVMAKLLQRIEFRLVP 464
            :|:||::|.:::  .|:::|
  Fly   463 LEIKVLLAAVIR--NFKILP 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp46a1	NP_034140.1	CYP46A1-like	61..484	CDD:410706	103/410 (25%)
Cyp4ac2	NP_608917.3	CYP4	84..503	CDD:410721	103/410 (25%)