Protein Alignment Cyp46a1 and Cyp4ac1

DIOPT Version :9

• Sequence 1: NP_034140.1
• Gene: Cyp46a1 / 13116
• MGIID: 1341877
• Length: 500
• Species: Mus musculus
• Sequence 2: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 419
• Identity: 109/419 - (26%)
• Similarity: 202/419 - (48%)
• Gaps: 48/419 - (11%)

Mouse    67 WAKKYGPVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSECDY 131
            |...|.|:..          |..||..::...|||....:.:|..::...|:     ||:...|:
  Fly    88 WYFLYAPMYN----------VVRPEEAEEVFQSTKLITKNVVYELIRPFLGD-----GLLISTDH 137

Mouse   132 GRWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTCATIDILAKAA 196
             :|:.:||.:..||..:.|.|.:..|.|:.::.:.:||...|.:  :.:..::...|::.:.:.|
  Fly   138 -KWHSRRKALTPAFHFNVLQSFLGIFKEECKKFLNVLEKNLDAE--LELNQVIPPFTLNNICETA 199

Mouse   197 FGME-TSMLLGAQ--KPLSQAVKVMLEGISASRNTLAK-----FMPGK-RKQLREIRESIRLLRQ 252
            .|:: ..|..|.:  |.:....:|:::.:.   |.|..     |:.|. ||.|    :::|::..
  Fly   200 LGVKLDDMSEGNEYRKAIHAIEEVLIQRVC---NPLMYYNWYFFVYGDYRKHL----QNLRIVHD 257

Mouse   253 VGKDWVQRRREALKR---------GEDMPADILTQILKAE-EGAQDDEVLLDNFVTFFIAGHETS 307
            .....::|:|:..::         |......:|..:|.|| :|..|.:.:.|...||...|::|:
  Fly   258 FSSRIIERKRQQFQQKQLGEVDEFGRKQRYAMLDTLLAAEADGQIDHQGICDEVNTFMFEGYDTT 322

Mouse   308 ANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRHLDYEDLGRLQYLSQVLKESLRLYPPAWGTFR 372
            :..|.||::.|:...::..:...||:.:......:......:|.||..|:|||||::|......|
  Fly   323 STCLIFTLLMLALHEDVQKKCYEEVENLPEDSDDISMFQFNKLVYLECVIKESLRMFPSVPFIGR 387

Mouse   373 LLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGAPKPR--FTYFPFSLGHR 435
            ...|||:::|:.:|.:|.:....|.:.|...:|..|..|.||||.|.....|  |.|.|||.|.|
  Fly   388 QCVEETVVNGMVMPKDTQISIHIYDIMRDPRHFPKPDLFQPDRFLPENTVNRHPFAYVPFSAGQR 452

Mouse   436 SCIGQQFAQMEVKVVMAKLLQRIEFRLVP 464
            :||||:||.:|:||::|.:::  .|:|:|
  Fly   453 NCIGQKFAILEMKVLLAAVIR--NFKLLP 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp46a1	NP_034140.1	p450	34..466	CDD:278495	109/419 (26%)
Cyp4ac1	NP_608916.1	p450	86..504	CDD:278495	109/419 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910