Protein Alignment Cyp46a1 and Cyp318a1

DIOPT Version :9

• Sequence 1: NP_034140.1
• Gene: Cyp46a1 / 13116
• MGIID: 1341877
• Length: 500
• Species: Mus musculus
• Sequence 2: NP_727590.1
• Gene: Cyp318a1 / 32172
• FlyBaseID: FBgn0030369
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 418
• Identity: 101/418 - (24%)
• Similarity: 186/418 - (44%)
• Gaps: 68/418 - (16%)

Mouse   133 RWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKAD--GQTP--VSMQDMLTCATIDILA 193
            :|..:||.::.|||.:.:.|..:.||....|:||..:.:.:  ||..  .:.:|:|:.|.:::..
  Fly   122 KWKLRRKQLNPAFSHNIVASFFDVFNSVGNQMVEQFQTQTNLHGQAVKFTAAEDLLSRAVLEVSC 186

Mouse   194 KAAFGMETSMLLGAQKPLSQAVKVMLEGISASR------------NTLAKFMPGKRKQLREIRES 246
            ....|..|:........::.:.|.:|| |||.|            ..||..:..:.|:..::.|.
  Fly   187 LTIMGTPTNFTQLDDAHIAHSYKRLLE-ISAVRVVKPWLQIRLLHRLLAPELYEESKKCAKLLED 250

Mouse   247 I--RLLRQVGKDWVQRRREAL---KRGEDMPAD-----ILTQILK-AEEGAQDDEVLLDNFVTFF 300
            .  .::|...::|  |.|:|:   |.|||....     .:.||.: |..|....|.::|...:..
  Fly   251 FVGGIVRTKHRNW--RLRDAVGGEKSGEDASNGWQRRIFIEQIFQLAANGEMTLEEIMDEAQSMV 313

Mouse   301 IAGHETSANHLAFTVMEL-SRQPEIVARLQAEVDEVVGSKRHLDYEDLGRLQYLSQVLKESLRLY 364
            :...||.:|.:...::.| :.:.:...||.||:..:|.....:..|.|.:|:||...:.|||||.
  Fly   314 LVSFETVSNSIMLALLCLATNKGDCQRRLLAEIRALVPDVGQVGLEQLQQLRYLDAFVSESLRLL 378

Mouse   365 PPAWGTFRLLEEETLIDGVR----VPGNTPLLFSTYVMGRMDTYF-EDPLTFNPDRF-------- 416
            .......|.:..:..:.|.:    ||.|:.::..|:.|.|.:.:: .:...|:|.||
  Fly   379 ATVPMNLRHVSRDFRLAGRQHETIVPQNSIVVLDTFNMQRDERWWGANARQFDPQRFLDQEEEQL 443

Mouse   417 -------GPGAPKPR------FTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRLVPGQRF 468
                   |.|..:.:      :::.|||.|.|||||:::....:||.:.||:...:|:    ..|
  Fly   444 SKGHNDSGSGEKRRQRDRRHSYSFLPFSNGLRSCIGRRYGLFIMKVFLVKLITNFDFQ----SDF 504

Mouse   469 GLQ-----EQATL--KPLDPVLCTLRPR 489
            .|:     |..:|  |..|.:|.|::|:
  Fly   505 ELEKLQFVENISLKFKNADDILLTIQPK 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp46a1	NP_034140.1	p450	34..466	CDD:278495	92/386 (24%)
Cyp318a1	NP_727590.1	p450	42..503	CDD:299894	92/387 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000