Protein Alignment Cyp46a1 and Cyp311a1

DIOPT Version :9

• Sequence 1: NP_034140.1
• Gene: Cyp46a1 / 13116
• MGIID: 1341877
• Length: 500
• Species: Mus musculus
• Sequence 2: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 503
• Identity: 130/503 - (25%)
• Similarity: 217/503 - (43%)
• Gaps: 83/503 - (16%)

Mouse     5 LLLLGSAVLLAFGLCCTFVHRARSRYEHIPGP---PRPSFLLGHLPYFWKKDEDCGRVLQD---- 62
            ||.|||:                     :|||   |    |||:.       :..|::..:
  Fly    22 LLRLGSS---------------------LPGPWAFP----LLGNA-------QMVGKLRPEYIFL 54

Mouse    63 VFLDWAKKYGPVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVS 127
            ||.:...::|...|:.:..:..|.:.|.|..::.|      .|..:.:|...:..|.|.|.||:
  Fly    55 VFTELRDRFGATYRLRLGPQLWVFLHSAEETRQAL------HDPTLRKADTFMQLEPLIGNGLL- 112

Mouse   128 ECDYG-RWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTCATIDI 191
             ..:| .|.:||:::..||....|.|.........|:||..|.|.......|: :.:..| .:|.
  Fly   113 -ISHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVGRLGATRGAFLEVT-EPLFAC-LLDA 174

Mouse   192 LAKAAFGMETSMLLGAQKPLSQAVKVMLEGISASRNTLAKFMPG---------KRKQL-REIRES 246
            :...:.|.:.........|:.||..:       |...|.|.|..         :|.|| |::.|.
  Fly   175 IVDTSMGAQLDTQSVDHSPIIQAFHL-------SSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQ 232

Mouse   247 IRLLRQVGKDWVQRR-REALKRGEDMPA----DILTQILKAE-EG-AQDDEVLLDNFVTFFIAGH 304
            ::::....:..:::| :|.|..||  ||    ::|..:|.|: || :.....:.|...||..||.
  Fly   233 LQVIHSQMESVIEKRAKELLDMGE--PAGRAHNLLDTLLLAKFEGQSLSRREIRDEINTFVFAGV 295

Mouse   305 ETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRHLDYEDLGRLQYLSQVLKESLRLYPPAWG 369
            :|:...::|.:..|::.||...||:.|:.:|...:. .|.:.|..|.||..::||.||||.....
  Fly   296 DTTTAAMSFVLYALAKFPETQTRLRKELQDVALDET-TDLDALNGLPYLEALIKEVLRLYTIVPT 359

Mouse   370 TFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRF----GPGAPKPRFTYFPF 430
            |.|...:.|.|.|........|..:.|.:.....|:.||..|.|:|:    |..|| |.|:|.||
  Fly   360 TGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAP-PAFSYIPF 423

Mouse   431 SLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRLVPGQR-FGLQEQATLK 477
            |.|...|||::::.:.:|::.|:|::..:..|.|.|. ..|:.|..||
  Fly   424 SGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLK 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp46a1	NP_034140.1	p450	34..466	CDD:278495	120/460 (26%)
Cyp311a1	NP_572780.3	p450	30..480	CDD:278495	125/474 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000