Protein Alignment Cyp46a1 and Cyp4g1

DIOPT Version :9

• Sequence 1: NP_034140.1
• Gene: Cyp46a1 / 13116
• MGIID: 1341877
• Length: 500
• Species: Mus musculus
• Sequence 2: NP_525031.1
• Gene: Cyp4g1 / 30986
• FlyBaseID: FBgn0010019
• Length: 556
• Species: Drosophila melanogaster
• Alignment Length: 516
• Identity: 119/516 - (23%)
• Similarity: 226/516 - (43%)
• Gaps: 85/516 - (16%)

Mouse     2 SPGL-LLLGSAVLLAFGLCCTFVHRARSRYEH-----IPGPPRPSFLLGHLPYFWKKDEDCGRVL 60
            ||.| .|:|:.|.:|.     :.:..|:..|:     ||.||       .||...:.....|...
  Fly    25 SPMLTTLVGTLVAMAL-----YEYWRRNSREYRMVANIPSPP-------ELPILGQAHVAAGLSN 77

Mouse    61 QDVF---LDWAKKYGPVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFG 122
            .::.   |.:..|||..::..:.....|.:|:|..::..|...::...::.||..:..||:.|
  Fly    78 AEILAVGLGYLNKYGETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKPWFGDGL-- 140

Mouse   123 QGLVSECDYGRWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTCA 187
              |:|...:  |...||::...|.:|.|.|.:.||.:.::.:|..:..:| |:: ..:.|.::..
  Fly   141 --LISNGHH--WRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLEA-GKS-FDVHDYMSQT 199

Mouse   188 TIDILAKAAFGMETSMLLGAQKPLSQAVKVMLEGISASR-------NTLAKFMPGKRKQLREIRE 245
            |:|||...|.|::...........:|||..|.:.|...:       :::.||...:.|..|.:..
  Fly   200 TVDILLSTAMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYKFTKLREKGDRMMNI 264

Mouse   246 SIRLLRQVGKDWVQRRREALKRG-----EDMPADILTQILKAEEGAQDD---------------- 289
            .:.:..:|.||    |:|..:..     |::...:.:.....:||.:||
  Fly   265 ILGMTSKVVKD----RKENFQEESRAIVEEISTPVASTPASKKEGLRDDLDDIDENDVGAKRRLA 325

Mouse   290 ------------------EVLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVV 336
                              :.::|...|....||:|::...:|.:..:....:|.|::.||...:.
  Fly   326 LLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIF 390

Mouse   337 GSK--RHLDYEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEE-TLIDG-VRVPGNTPLLFSTYV 397
            |..  |...:.|...::||.:|:.|:||||||.....|.|:.: .|..| ..||..|.::...|.
  Fly   391 GDNMLRDCTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYC 455

Mouse   398 MGRMDTYFEDPLTFNPDRFGPG--APKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQ 456
            :.|....:.:|..|:||.|.|.  |.:..:::.|||.|.|||:|:::|.:::||:::.:::
  Fly   456 VHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVR 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp46a1	NP_034140.1	p450	34..466	CDD:278495	109/478 (23%)
Cyp4g1	NP_525031.1	p450	58..518	CDD:278495	109/478 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000