Protein Alignment Cyp3a16 and Cyp6d4

DIOPT Version :10

• Sequence 1: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Sequence 2: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Alignment Length: 545
• Identity: 180/545 - (33%)
• Similarity: 289/545 - (53%)
• Gaps: 92/545 - (16%)

Mouse    11 TLVLLAIILVLL--------YRYGTCTHGLFKKQGIPGPK--PLPF--LGTVLNYYKGLWKFDME 63
            :|:|||:.|:.|        |.|       ::::|.|..|  .:||  |.:|....|.:   .:.
  Fly     3 SLILLAVTLLTLAWFYLKRHYEY-------WERRGFPFEKHSGIPFGCLDSVWRQEKSM---GLA 57

Mouse    64 CYEKYGKT----WGLFDGQIPLFVITDPETIKNVLVKECFSVFTNRQDFFPVGI--------MSK 116
            .|:.|.|:    .|::....|..:|.|.:..:.||.:: |:.|.:|      |:        :|.
  Fly    58 IYDVYVKSKERVLGIYLLFRPAVLIRDADLARRVLAQD-FASFHDR------GVYVDEERDPLSA 115

Mouse   117 SISLAKDEEWKRYRALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQE-AEKG-KPVAVKDVLGAY 179
            :|...:.:.|:..|.:|||.||||.||.||...|..||.:|.:|::| .|:| |.|.:|.|:..|
  Fly   116 NIFSLRGQSWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEVDIKKVMQNY 180

Mouse   180 SMDVIISTTFGVNIDSLNNPEDPF---VENAKKVLRFDYFDPLSL----SVALFPFLTPIYEMLN 237
            ::|:|.||.||::::|..||::.|   |..|:...||:....:.:    |:|.|.|.......:.
  Fly   181 AIDIIASTIFGLDVNSFENPDNKFRKLVSLARANNRFNAMFGMMIFLVPSIAQFLFRIGFKNPVG 245

Mouse   238 ICMFP--KDSIEFFKKFVDRMTENRLDSKQKH---RVDFIYLMMEAYN---------KS----KD 284
            :.|..  |:::|:               ::||   |.|.:.|:::..|         ||    |.
  Fly   246 LAMLQIVKETVEY---------------REKHGIVRKDLLQLLIQLRNTGKIDENDEKSFSIQKT 295

Mouse   285 KDSH-KALSEIEITAQSIIFIFAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEAL-PNKAPPT 347
            .|.| |.:|...||||:.||..||.|||.|..:||:|.||.:|::.|:||:|:||.| .|....|
  Fly   296 PDGHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKIT 360

Mouse   348 YDTVMAMEYLDMVLNETLRLYPITNRLQRVCKKDVEI---NGIYIPKGSTVIIPSYVLHHDPQHW 409
            ||::..||:||:.:.||:|.||....|.|.|.:|..:   |.: ||||:.|:|..|.:|||.:::
  Fly   361 YDSLNKMEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHV-IPKGTPVVISLYGIHHDAEYF 424

Mouse   410 PEPEEFQPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKETQI 474
            |:||.:.|||||:|:: :.:|..::|||.|||.||..|...:|.|||:||:||||:.:....::|
  Fly   425 PDPETYDPERFSEESR-NYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSEI 488

Mouse   475 PLKLSRELLL--QPVKPIVLKVVPR 497
            ..:.|...|:  ..|:..:.|.||:
  Fly   489 EFENSGIALIPKHGVRVRLSKRVPK 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a16	NP_031846.2	CYP3A	67..493	CDD:410743	160/471 (34%)
Cyp6d4	NP_651082.1	CYP6-like	66..504	CDD:410679	157/461 (34%)