Protein Alignment Cyp3a16 and Cyp6a19

DIOPT Version :9

• Sequence 1: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Sequence 2: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 539
• Identity: 161/539 - (29%)
• Similarity: 270/539 - (50%)
• Gaps: 77/539 - (14%)

Mouse     1 MNLFSALSLDTLVLLAIILVLLYRYGTCTHGLFKKQGIPGPKPLPFLGTVLNYYK-----GLWKF 60
            |.:...|.:..|.|:|..::..|.|       :|::|||...|...||.....::     |:.|
  Fly     1 MAILLGLVVGVLTLVAWWVLQNYTY-------WKRRGIPHDPPNIPLGNTGELWRTMPLAGILK- 57

Mouse    61 DMECYEKYGK-TWGLFDG----QIPLFVITDPETIKNVLVKECFSVFTNRQDFFPVGI------- 113
              ..|.|:.| |.|.|.|    .:...||||.:.:|.||::: |..|.:|      |:
  Fly    58 --RTYLKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRD-FDKFHDR------GVYHNEKDD 113

Mouse   114 -MSKSISLAKDEEWKRYRALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQE-AEKGKPVAVKDVL 176
             ::.:::..:.::||..|..|:.||||..:|.||..:...||.:::.:.:: :...:.:.|.|::
  Fly   114 PLTNNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIV 178

Mouse   177 GAYSMDVIISTTFGVNIDSLNNPEDPFVENAKKVLR---------FDYFDPLSLSVAL-FPFLTP 231
            ..::.|||....||:..:||.:|:..||:.....||         ...|....|:|.| |.||.|
  Fly   179 SRFTSDVIGICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLP 243

Mouse   232 IYEMLNICMFPKDSIEFFKKFVDRMTENRLDSKQKHRV------DFIYLMMEAYNKSKDKDSHKA 290
                         |::   ||..::.::.:|.:.|.:|      |.:..|.:.|:|. ||::..|
  Fly   244 -------------SVQ---KFYMKIVQDTIDYRMKRKVTRNDFMDTLIDMKQQYDKG-DKENGLA 291

Mouse   291 LSEIEITAQSIIFIFAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPN-KAPPTYDTVMAM 354
            .:  |:.||:.:|..||:|..|:.:.||:|.||.:.|:|.||:.|||..|.. .....||::..:
  Fly   292 FN--EVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDL 354

Mouse   355 EYLDMVLNETLRLYPITNRLQRVCKKDVEING--IYIPKGSTVIIPSYVLHHDPQHWPEPEEFQP 417
            .|::.|:||:||.:|:...|.|:..|..:.:.  .:|..|:.|::.:..:||||:.:||||:|.|
  Fly   355 FYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIP 419

Mouse   418 ERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKETQIPLKLS-RE 481
            |||.:|.........:||||.|||||||:||..|.:.:.|..::.||.|:...:|.:|:|.: ..
  Fly   420 ERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYTINN 484

Mouse   482 LLLQPVKPIVLKV--VPRD 498
            |||.....|.|.:  |.||
  Fly   485 LLLGSEGGIHLNITKVVRD 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a16	NP_031846.2	p450	39..494	CDD:278495	148/493 (30%)
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	147/491 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.720