Protein Alignment Cyp3a16 and Cyp6a14

DIOPT Version :10

• Sequence 1: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Sequence 2: NP_610389.3
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 520
• Identity: 179/520 - (34%)
• Similarity: 270/520 - (51%)
• Gaps: 49/520 - (9%)

Mouse     9 LDTLVLLAIILVLLYRYGTCTHGLFKKQGIPGPKPLPFLGTVLNYYKGLWK------FDMECYEK 67
            |.|:.|:.::|.|.|.........:|::|:|...|||.:|.:    :|:.|      .:...|:|
  Fly     2 LFTIALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLPIVGNM----RGIVKKYHFRDINQRIYKK 62

Mouse    68 YGKTWGLFDGQIPLF----VITDPETIKNVLVKECFS------VFTNRQDFFPVGIMSKSISLAK 122
            : |..|...|....|    :|||.:.||.|::|: ||      .|||.:|    ..::..:...:
  Fly    63 F-KGQGPIAGMYMFFKRTALITDLDFIKQVMIKD-FSYFQDRGAFTNPRD----DPLTGHLFALE 121

Mouse   123 DEEWKRYRALLSPTFTSGNLKEMFPVIE----QYGDILVKYLRQ-EAEKGKPVAVKDVLGAYSMD 182
            .|||:..|..|:|.||||.:|:|..||.    :.||.:.|.::: :.|:|. |.:||:...::.|
  Fly   122 GEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGN-VEIKDLCARFTTD 185

Mouse   183 VIISTTFGVNIDSLNNPEDPFVENAKKVLRFDYFDPLSLSVALFPFLTP-IYEMLNICMFPKDSI 246
            ||.|..||:..:||.:|...|.:..:::........|   |..|.|... :...|.|.:.|.|..
  Fly   186 VIGSCAFGLECNSLQDPSAEFRQKGREIFTRRRHSTL---VQSFIFTNARLARKLRIKVLPDDLT 247

Mouse   247 EFFKKFVDRMTENRLDSKQKHRVDFIYLMM-------EAYNKSKDKDSHKALSEIEITAQSIIFI 304
            :||...|....:.||.:..| |.|||..|:       ||..|.:..|....|:..::.||:.:|.
  Fly   248 QFFMSTVKNTVDYRLKNGIK-RNDFIEQMIELRAEDQEAAKKGQGIDLSHGLTLEQMAAQAFVFF 311

Mouse   305 FAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPN--KAPPTYDTVMAMEYLDMVLNETLRL 367
            .||:||:||.:|..:|.||..||||::|:|||:..|.|  .....||.:..|.|||.||:||||.
  Fly   312 VAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSETLRK 376

Mouse   368 YPITNRLQRVCKKDVEI--NGIYIPKGSTVIIPSYVLHHDPQHWPEPEEFQPERFSKENKGSIDP 430
            :|:...|.|...||.:|  :.|.:.||...:||.:.:||||:.:||||:|.|.||..|...:..|
  Fly   377 HPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEVKNRHP 441

Mouse   431 YVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKETQIPLKLSRE-LLLQPVKPIVLKV 494
            ..|||||:|||||||:||..:..|:.|:.:|:.|.|.....|.:||..|:: .||.....|.|||
  Fly   442 MAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKSFLLTTNDGIYLKV 506

Mouse   495  494
              Fly   507  506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a16	NP_031846.2	CYP3A	67..493	CDD:410743	160/453 (35%)
Cyp6a14	NP_610389.3	CYP6-like	65..503	CDD:410679	157/447 (35%)