Protein Alignment Cyp3a16 and Cyp6t1

DIOPT Version :10

• Sequence 1: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Sequence 2: NP_608457.1
• Gene: Cyp6t1 / 33127
• FlyBaseID: FBgn0031182
• Length: 529
• Species: Drosophila melanogaster
• Alignment Length: 533
• Identity: 153/533 - (28%)
• Similarity: 254/533 - (47%)
• Gaps: 73/533 - (13%)

Mouse     5 SALSLDTLVLLAIIL----------VLLYRYGTCTHGLFKKQGIPGPKPLPFLGTVLNYYKGLWK 59
            :||::.:||||.::|          |.|::.....|  :::.|:|.....||:|.|.|..:|...
  Fly    10 AALAVGSLVLLPVVLRGGCLLVVTIVWLWQILHFWH--WRRLGVPFVPAAPFVGNVWNLLRGACC 72

Mouse    60 FD---MECYEKYGKTWGLFDGQIPL----FVITDPETIKNVLVKECFSVFTNR-QDFFPV--GIM 114
            |.   .|.||........|.|...|    .::.||..||.::|:: |:.|::| :...|.  .:.
  Fly    73 FGDQFRELYESKEAAGRAFVGIDVLHNHALLLRDPALIKRIMVED-FAQFSSRFETTDPTCDTMG 136

Mouse   115 SKSISLAKDEEWKRYRALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQE--AEKGKPVAVKDVLG 177
            |:::..:|.|.|:....:.:|.|.:|.::.|:.::|..|..|.:::.|:  ......:.||.:..
  Fly   137 SQNLFFSKYETWRETHKIFAPFFAAGKVRNMYGLLENIGQKLEEHMEQKLSGRDSMELEVKQLCA 201

Mouse   178 AYSMDVIISTTFGVNIDSLNNPEDPF----VE----NAKKVLRFDYFDPLSLSVALFPFLTPIYE 234
            .::.|:|.|..||:...||.|||..|    :|    ..|::|..       .::..||.|:   .
  Fly   202 LFTTDIIASLAFGIEAHSLQNPEAEFRRMCIEVNDPRPKRLLHL-------FTMFFFPRLS---H 256

Mouse   235 MLNICMFPKDSIEFFKKFVDRMTENRLDS-KQKHRVDFIYLMMEAYNKSKDKDSHKALSEIE--- 295
            .:...::.::...|.:|.:|.:...|.:| :.:|.:..|:|.:        |.:..|.|.|.
  Fly   257 RVGTHLYSEEYERFMRKSMDYVLSQRAESGENRHDLIDIFLQL--------KRTEPAESIIHRPD 313

Mouse   296 -ITAQSIIFIFAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPNKAPP--TYDTVMAMEYL 357
             ..||:...:.||::|:||.::|.:|.||.:..||.:|:.|:..||.:....  :.|||..:.||
  Fly   314 FFAAQAAFLLLAGFDTSSSTITFALYELAKNTTIQDRLRTELRAALQSSQDRQLSCDTVTGLVYL 378

Mouse   358 DMVLNETLRLYPITNRLQRVCKKDVEI-----NG---IYIPKGSTVIIPSYVLHHDPQHWPEPEE 414
            ..|::|.|||||.|..|.|.|......     ||   ..:..|:.|.|....:|.|.|:||.||.
  Fly   379 RQVVDEVLRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFKLRAGTPVYISVLGIHRDAQYWPNPEV 443

Mouse   415 FQPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKETQIPLKLS 479
            |.|||||.|.:....|..|||||.|||.|||.....:.:|:.|:.:|.:|..:.|:.| :|
  Fly   444 FDPERFSAEQRQQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLLHILNHFRVEVCERT-LP---- 503

Mouse   480 RELLLQPVKPIVL 492
             |:...| |..||
  Fly   504 -EMRFDP-KAFVL 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a16	NP_031846.2	CYP3A	67..493	CDD:410743	131/458 (29%)
Cyp6t1	NP_608457.1	CYP6-like	88..521	CDD:410679	131/453 (29%)