Protein Alignment Cyp3a16 and Cyp4s3

DIOPT Version :9

• Sequence 1: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Sequence 2: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Alignment Length: 539
• Identity: 138/539 - (25%)
• Similarity: 248/539 - (46%)
• Gaps: 99/539 - (18%)

Mouse     9 LDTLVLLAIIL-VLLYRYGTCTHGLFKKQ----GIPGPKPLPFL-----GTVLNYYKGLWKFDME 63
            :.||.|:|.:| ....||........:.|    .:|||.....:     |.:||:.|       |
  Fly     1 MSTLALVAFVLWAAFLRYLPKILNFLRLQRFAKTLPGPTIGELIANVKKGEILNWLK-------E 58

Mouse    64 CYEKYGKTWGLFDGQIPLFVITDPETIKNVLVKECFSVFTNRQDF------FPVGIMSKSISLAK 122
            ..||:|..:.::.|:..:.:.||||.||.:|...  .:.|..:::      ...|:::..
  Fly    59 LREKHGPVFRIWFGKDLMVMFTDPEDIKQLLGNN--QLLTKSRNYELLEPWLGKGLLTNG----- 116

Mouse   123 DEEWKRYRALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQEAEKGKPVAVKDVLGAYSMDVIIST 187
            .|.|.|.|.||:|.|....|.|....:|:...|||:.||.:| .|:...:...:..:::|.|..|
  Fly   117 GESWHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRLRTKA-NGESFDIYPYITLFALDAICET 180

Mouse   188 TFGVNIDSLNNPEDPFVENAKKVLRFDYFDPLSLSVALFPFLTPIYEMLNICMFPKDSIEFFK-- 250
            ..|:...:....:..:|:..:.:.|..:....|           .::.||:         |||
  Fly   181 AMGIKKHAQLQSDSEYVQAVQSICRVMHKQSFS-----------FWQRLNV---------FFKHT 225

Mouse   251 --------------------------KFVDRMTENRLDSKQ-----KHRVDFIYLMMEAYNKSKD 284
                                      :.:....|.:.:::|     |.|:.|:.:::     ...
  Fly   226 KPGKEREAALKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLL-----LTQ 285

Mouse   285 KDSHKALSEIEITAQSIIFIFAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPNKAPPTYD 349
            .:....||:.:|..:...|:|.|::||||.::|.:..|:.:||:|::..||..|....:..
  Fly   286 MEGGAELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEGREKE---- 346

Mouse   350 TVMAMEYLDMVLNETLRLYPITNRLQRVCKKDVEINGIYIPKGSTVIIPSYVLHHDPQHWPEPEE 414
               :|.||:.|:.||||:||......|...:|:|:..:.:|||:::....|:||.||:::|:||.
  Fly   347 ---SMPYLEAVIKETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNFPDPER 408

Mouse   415 FQPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKETQIPLKLS 479
            |.|:|| ..|:..:.|:.:..|..|||||||.:||::.:|.:|..:|:::.|.|.|:.| |..|:
  Fly   409 FDPDRF-LVNEKQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFLPDKDHQ-PKPLA 471

Mouse   480 RELLLQPVKPIVLKVVPRD 498
             ||:.:....|.|:::|||
  Fly   472 -ELVTKSGNGIRLRILPRD 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a16	NP_031846.2	p450	39..494	CDD:278495	127/498 (26%)
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	122/482 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810