Protein Alignment Cyp3a13 and Cyp4e1

DIOPT Version :10

• Sequence 1: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Sequence 2: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Alignment Length: 522
• Identity: 133/522 - (25%)
• Similarity: 245/522 - (46%)
• Gaps: 82/522 - (15%)

Mouse    12 WMLLATSLVL-LYLYGTHSHGIFKKLGI----PGPKPLPFLGTILAYQK------------GFWE 59
            |::|...|.| |:|......|:.::..:    .||..||.:|.  |:|.            |:|.
  Fly     2 WIVLCAFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLVGN--AHQMGNTPTEILNRFFGWWH 64

Mouse    60 CDIQCHKKYGK----MW-GLYDGRQPVLAITDPDIIKTVLVKECY----STFTNRRRFGPVGILK 115
                   :|||    .| |.|..    :.:|:|..::.:|..:..    ..:.....:..:|:|
  Fly    65 -------EYGKDNFRYWIGYYSN----IMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLL- 117

Mouse   116 KAISISENEEWKRIRALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQGLGEGKPTSMKDIFGAYS 180
                .|...:|.:.|.:::|.|....|::...::|:.:...:..:::....|.....::.....:
  Fly   118 ----TSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLT 178

Mouse   181 MDVITATSFGVNIDSLNNPQDPFVEKIKKL---LKFDIFDPLFLSVTLFPFLTPVFDALNVSL-- 240
            :|||..|:.||:|:::.|.....|:..|.:   :|...|.|...:..||.| .|.:...:.:|
  Fly   179 LDVICDTAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHF-APEYPEYSKTLKT 242

Mouse   241 ---FPRDVISFFTTSVERMKEN-----RMKEKEKQRVDFLQLMINSQNYKTKESHKALSDVEIVA 297
               |..::|:   ..:|..|..     :..|..::::.||..:::|     |...:.|:..|:..
  Fly   243 LQDFTNEIIA---KRIEVRKSGLEVGIKADEFSRKKMAFLDTLLSS-----KVDGRPLTSQELYE 299

Mouse   298 QSVIFIFAGYETTSSALSFALYLLAIHPDVQKKL---QDEIDAALPNKAPATYDTLLQMEYLDMV 359
            :...|:|.|::||:|.:.||:|||:.|||.|:||   |.::..|......||:..:..|::||:.
  Fly   300 EVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLF 364

Mouse   360 VNETLRLYPIAGRLERVCKTDVEINGLFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSKKNQ 424
            :.|..||||....:.|..:.|..|:|..:||||.:.:....|..:.:.:.:|.:|:||||.::..
  Fly   365 IKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDREKP 429

Mouse   425 DSINPYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQPCKETEIPLKLSKQGL------L 483
               .|:.|:||.:|||||||.:|||:.:|..:.::::||.|.|..:..:    ||.|.      |
  Fly   430 ---GPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELV----SKDGYISTTLGL 487

Mouse   484 QP 485
            ||
  Fly   488 QP 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a13	NP_031845.1	CYP3A	67..492	CDD:410743	117/450 (26%)
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	115/447 (26%)