Protein Alignment Cyp3a13 and Cyp4d8

DIOPT Version :10

• Sequence 1: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Sequence 2: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Alignment Length: 499
• Identity: 133/499 - (26%)
• Similarity: 238/499 - (47%)
• Gaps: 67/499 - (13%)

Mouse    13 MLLATSLVLLYLYGTHSHGIFKKLG----------IPGPKPLPFLGT----ILAYQKGFWECDIQ 63
            |||...:|||:..|...|     ||          :|||...|.:|.    :....|.|.:...:
  Fly     1 MLLFLLVVLLFGAGWIIH-----LGQADRRRKVANLPGPICPPLIGAMQLMLRLNPKTFIKVGRE 60

Mouse    64 CHKKYGKMWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRFGPVG-ILKKAISISENEEWK 127
            ...|:|.:..::...:.::...|.::.:.:|..:  ........:..:| .|...:.:|:.:.|.
  Fly    61 YVLKFGHLQRVWIFNRLLIMSGDAELNEQLLSSQ--EHLVKHPVYKVLGQWLGNGLLLSDGKVWH 123

Mouse   128 RIRALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQGLGEGKPTSMKDIFGAYSMDVITATSFGVN 192
            :.|.:::|||....|::...:.:|.:::.|:.:.| ...|....:.....|.::|:|..|:.|..
  Fly   124 QRRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQ-KANGNTFDVYRSICAAALDIIAETAMGTK 187

Mouse   193 IDSLNNPQDPFVEKIKK---LLKFDIFDPLFLSVTLFPFLTPVFDALNVSLFPRDVISFFTTSVE 254
            |.:..|...|:.|.:.:   ||.:. |..::|.|.|      :|...:..|..|.     |..:.
  Fly   188 IYAQANESTPYAEAVNECTALLSWR-FMSVYLQVEL------LFTLTHPHLKWRQ-----TQLIR 240

Mouse   255 RMKENRMK--EKEKQRVDFLQ--LMINSQNYKTKESHKALSDV--------------EIVAQSVI 301
            .|:|..:|  ||.:|.::..|  ||..:......:...||.||              ||..:...
  Fly   241 TMQEFTIKVIEKRRQALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTVDGRPLTNDEIREEVDT 305

Mouse   302 FIFAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAAL--PNKAPATYDTLLQMEYLDMVVNETL 364
            |:|.|::||:|||||.|:.|:.||:||.|:.:||...|  ....|.:...|.:::|::.|:.|:|
  Fly   306 FMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESL 370

Mouse   365 RLYPIAGRLERVCKTD------VEINGLFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSKKN 423
            |:||....:.|..:||      |..:|: ||.|:.::|..|.:|:.|:.:|.|:||.|||  .:|
  Fly   371 RMYPPVPIVGRKLQTDFKYTHSVHGDGV-IPAGSEIIIGIFGVHRQPETFPNPDEFIPER--HEN 432

Mouse   424 QDSINPYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQP 467
            ...:.|:..:||.:|||||||.:||.:.||:.|.::::.:.:.|
  Fly   433 GSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLP 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a13	NP_031845.1	CYP3A	67..492	CDD:410743	116/431 (27%)
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	115/429 (27%)