Protein Alignment Cyp3a13 and Cyp6a23

DIOPT Version :9

• Sequence 1: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Sequence 2: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Alignment Length: 509
• Identity: 180/509 - (35%)
• Similarity: 273/509 - (53%)
• Gaps: 47/509 - (9%)

Mouse    14 LLATSLVLLYLYGTHSHGIFKKLGIPGPKPLPFLGTILAYQKGFWECDI--QCHKKYGK----MW 72
            |:|..:.||.......||.:::.|||...|.|..|.:..:.|......|  ..:.||.:    ..
  Fly     7 LIALLVSLLLFMARRRHGYWQRRGIPHDVPHPIYGNMKDWPKKRHIAMIFRDYYTKYKRSVYPFA 71

Mouse    73 GLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRF-----GPVGILKKAISISENEEWKRIRAL 132
            |.|........|||.:::|.||:|: ::.|.||..|     .|   |...:...|.::|:.:|..
  Fly    72 GFYFFFTRSAVITDLELVKRVLIKD-FNHFENRGIFYNEIDDP---LSATLFSIEGQKWRHLRHK 132

Mouse   133 LSPTFTSGRLKEMFPIINQFTDVL--VRNMRQGLGEGKPTSMKDIFGAYSMDVITATSFGVNIDS 195
            |:||||||::|.|||||.:..:.:  :.:.:...|||:...:.|:...|:.|||...:||:|.:|
  Fly   133 LTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQVLEIVDLVARYTADVIGNCAFGLNCNS 197

Mouse   196 LNNPQDPFVEKIKK---------LLKFDIFDPLFLSVTLFPFLTPVFDALNVSLFPRDVISFFTT 251
            |.||...||...|:         ||.|.||.        ||.|:   ..|.:.|..:||..|:|:
  Fly   198 LQNPNAEFVTIGKRAIIERRYGGLLDFLIFG--------FPKLS---RRLRLKLNVQDVEDFYTS 251

Mouse   252 SVERMKENRMKEKEKQRVDFLQLMINSQNYKTKE---SHKALSDVEIVAQSVIFIFAGYETTSSA 313
            .|....:.|::..|| |.||:..:|  :.|:.::   :...||..||:||:.||..||:||:|:.
  Fly   252 IVRNTIDYRLRTNEK-RHDFMDSLI--EMYEKEQAGNTEDGLSFNEILAQAFIFFVAGFETSSTT 313

Mouse   314 LSFALYLLAIHPDVQKKLQDEIDAAL-PNKAPATYDTLLQMEYLDMVVNETLRLYPIAGRLERVC 377
            :.||||.||:..|:|.:|:.||:..| .:....||:.:.:|:||:.||.||||.||:...|.|:.
  Fly   314 MGFALYELALDQDIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMT 378

Mouse   378 KTDV--EINGLFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSKKNQDSINPYMYLPFGSGPR 440
            :||.  |....||.|||.|:||...:|.||:.:||||:|:||||:.:...:.....:||||.|||
  Fly   379 QTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPR 443

Mouse   441 NCIGMRFALINMKVALVRVLQNFTVQPCKETEIPLK-LSKQGLLQPENPLLLKV 493
            ||||:||.|:...|.|..:::.:......||:||:| :.|..||..||.:.|||
  Fly   444 NCIGLRFGLMQACVGLAYLIRGYKFSVSTETQIPMKFVVKSILLSAENGIHLKV 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a13	NP_031845.1	p450	39..491	CDD:365848	169/480 (35%)
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	168/476 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2429
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.740