Protein Alignment Cyp3a13 and Cyp6t3

DIOPT Version :10

• Sequence 1: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Sequence 2: NP_610745.1
• Gene: Cyp6t3 / 36318
• FlyBaseID: FBgn0033697
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 516
• Identity: 149/516 - (28%)
• Similarity: 247/516 - (47%)
• Gaps: 60/516 - (11%)

Mouse    12 WMLLATSLVLLYLYGTHSHGIFKKLGIP-----GPKPLPFLGTILAYQKGFWECDIQCH----KK 67
            |:||.| :|.|..:..|.:..|:..|||     ...|:..||.:|..:..|.:...|.:    ..
  Fly     5 WLLLLT-IVTLNFWLRHKYDYFRSRGIPHLPPSSWSPMGNLGQLLFLRISFGDLFRQLYADPRNG 68

Mouse    68 YGKMWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRFG----PVGILKKAISISENEEWKR 128
            ..|:.|.:..:.|.|.:.||::|:.||:|. ::.|.||....    |:|.|  .:.:::...||.
  Fly    69 QAKIVGFFIFQTPALMVRDPELIRQVLIKN-FNNFLNRFESADAGDPMGAL--TLPLAKYHHWKE 130

Mouse   129 IRALLSPTFTSGRLKEMFPIINQFTDV---LVRNMRQGLGE--------GKPTSMKDIFGAYSMD 182
            .|..:|..|||||::::  :.:|..||   |.:.:.:.||:        |:...:      |:.|
  Fly   131 SRQCMSQLFTSGRMRDV--MYSQMLDVASDLEQYLNRKLGDRLERVLPLGRMCQL------YTTD 187

Mouse   183 VITATSFGVNIDSLNNPQDPFVEKIKKLLKFD---IFDPLFLSVTLFPFLTPVFDALNVSLFPRD 244
            |.....:.:|:..|...:...:.|.|:|...:   :.|  |:||...|..|.|   |...:|..|
  Fly   188 VTGNLFYSLNVGGLRRGRSELITKTKELFNTNPRKVLD--FMSVFFLPKWTGV---LKPKVFTED 247

Mouse   245 VISFFTTSVERMKENRMKEKEKQRVDFLQLMINSQNYKTKESHKALSDVEIVAQSVIFIFAGYET 309
            ...:....|:...|....:...|...| ||..:|.:|......       :.:|:.|.:.||:||
  Fly   248 YARYMRHLVDDHHEPTKGDLINQLQHF-QLSRSSNHYSQHPDF-------VASQAGIILLAGFET 304

Mouse   310 TSSALSFALYLLAIHPDVQKKLQDEIDAALPNKAPATYDTLLQMEYLDMVVNETLRLYPIAGRLE 374
            :|:.:.|.||.||..||:|::|:.|:..|..:.|..:||||:.:.||.||..|.|||||.|..:.
  Fly   305 SSALMGFTLYELAKAPDIQERLRSELREAFISTATLSYDTLMTLPYLKMVCLEALRLYPAAAFVN 369

Mouse   375 RVCKTDVEIN-------GLFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSKKNQDSINPYMY 432
            |.|.:.....       ...:|.|....|....||:|.::||||..|.||||..:....|:|..|
  Fly   370 RECTSSASEGFSLQPHVDFIVPPGMPAYISILGLHRDERFWPEPCVFDPERFGPERSRHIHPMTY 434

Mouse   433 LPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQPCKETEIPLKLS-KQGLLQPENPLLLK 492
            :|||:||..|||.|..::.:|:.:|.:|:.:.|:.|:.|...::.: |..:|:.||.:.|:
  Fly   435 IPFGAGPHGCIGSRLGVLQLKLGIVHILKQYWVETCERTVSEIRFNPKSFMLESENEIYLR 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a13	NP_031845.1	CYP3A	67..492	CDD:410743	131/450 (29%)
Cyp6t3	NP_610745.1	CYP6-like	68..493	CDD:410679	131/448 (29%)