Protein Alignment Cyp3a13 and Cyp6t1

DIOPT Version :10

• Sequence 1: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Sequence 2: NP_608457.1
• Gene: Cyp6t1 / 33127
• FlyBaseID: FBgn0031182
• Length: 529
• Species: Drosophila melanogaster
• Alignment Length: 544
• Identity: 148/544 - (27%)
• Similarity: 257/544 - (47%)
• Gaps: 71/544 - (13%)

Mouse     3 LIPNFSMETWMLLATSLVLL---------------YLYGTHSHGIFKKLGIPGPKPLPFLGTILA 52
            :|..||:....|...|||||               :|:.......:::||:|.....||:|.:..
  Fly     1 MIAVFSLIAAALAVGSLVLLPVVLRGGCLLVVTIVWLWQILHFWHWRRLGVPFVPAAPFVGNVWN 65

Mouse    53 YQKGFWECDIQCHKKYGKMW-GLYDGRQP--------------VLAITDPDIIKTVLVKECYSTF 102
            ..:|  .|   |   :|..: .||:.::.              .|.:.||.:||.::|:: ::.|
  Fly    66 LLRG--AC---C---FGDQFRELYESKEAAGRAFVGIDVLHNHALLLRDPALIKRIMVED-FAQF 121

Mouse   103 TNR-RRFGP----VGILKKAISISENEEWKRIRALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQ 162
            ::| ....|    :|  .:.:..|:.|.|:....:.:|.|.:|:::.|:.::......|..:|.|
  Fly   122 SSRFETTDPTCDTMG--SQNLFFSKYETWRETHKIFAPFFAAGKVRNMYGLLENIGQKLEEHMEQ 184

Mouse   163 GLG--EGKPTSMKDIFGAYSMDVITATSFGVNIDSLNNPQDPFVEKIKKLLKFDIFDP----LFL 221
            .|.  :.....:|.:...::.|:|.:.:||:...||.||:..|     :.:..::.||    |..
  Fly   185 KLSGRDSMELEVKQLCALFTTDIIASLAFGIEAHSLQNPEAEF-----RRMCIEVNDPRPKRLLH 244

Mouse   222 SVTLFPFLTPVFDALNVSLFPRDVISFFTTSVERMKENRMKEKEKQRVDFLQLMINSQNYKTKES 286
            ..|:| |...:...:...|:..:...|...|::.:...| .|..:.|.|.:.:.:..:..:..||
  Fly   245 LFTMF-FFPRLSHRVGTHLYSEEYERFMRKSMDYVLSQR-AESGENRHDLIDIFLQLKRTEPAES 307

Mouse   287 HKALSDVEIVAQSVIFIFAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAALPNK--APATYDT 349
            .....|. ..||:...:.||::|:||.::||||.||.:..:|.:|:.|:.|||.:.  ...:.||
  Fly   308 IIHRPDF-FAAQAAFLLLAGFDTSSSTITFALYELAKNTTIQDRLRTELRAALQSSQDRQLSCDT 371

Mouse   350 LLQMEYLDMVVNETLRLYPIAGRLERVC--KTDVEI---NG---LFIPKGTVVMIPTFALHKDPK 406
            :..:.||..||:|.|||||....|:|.|  :|..::   ||   ..:..||.|.|....:|:|.:
  Fly   372 VTGLVYLRQVVDEVLRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFKLRAGTPVYISVLGIHRDAQ 436

Mouse   407 YWPEPEEFRPERFSKKNQDSINPYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQPCKET 471
            |||.||.|.|||||.:.:...:|..|||||:|||.|||.....:.:||.|:.:|.:|.|:.|:.|
  Fly   437 YWPNPEVFDPERFSAEQRQQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLLHILNHFRVEVCERT 501

Mouse   472 EIPLKLS-KQGLLQPENPLLLKVV 494
            ...::.. |..:|...|...|:.|
  Fly   502 LPEMRFDPKAFVLTAHNGTYLRFV 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a13	NP_031845.1	CYP3A	67..492	CDD:410743	127/461 (28%)
Cyp6t1	NP_608457.1	CYP6-like	88..521	CDD:410679	124/443 (28%)