Protein Alignment Cyp3a13 and Cyp4d2

DIOPT Version :10

• Sequence 1: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Sequence 2: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 491
• Identity: 150/491 - (30%)
• Similarity: 255/491 - (51%)
• Gaps: 61/491 - (12%)

Mouse    13 MLLATSLVLL--YLYGTHSHGIFKKLGIPGPKPLPFLGTILAYQ----KGFWECDIQCHKKYGKM 71
            :|:|.:.:||  :|:....:||     :|||:||||||.:|.|:    :...:...:..:|||::
  Fly     9 LLVAFATLLLWDFLWRRRGNGI-----LPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKYGRL 68

Mouse    72 WGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRFGPVGILKKAIS--------ISENEEWKR 128
            :.::...|..:..|||..|:.||..:.:.|..|         |.|.::        :|...:|..
  Fly    69 YRVWILHQLAVFSTDPRDIEFVLSSQQHITKNN---------LYKLLNCWLGDGLLMSTGRKWHG 124

Mouse   129 IRALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQGLGEGKPTSMKDIFGAYSMDVITATSFGVNI 193
            .|.:::|||....|::...|.:|.:.|:|..::.......|.::..:....::|:|..|:.|..|
  Fly   125 RRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKI 189

Mouse   194 DSLNNPQDPFVEKIKKLLKFDI--FDPLFLSVTLFPFLTPVFDALNVSLFPRD----VISFFT-- 250
            ::..||..|:|:.:..:....|  |...:..|.....||...:|..     :|    |:..||
  Fly   190 NAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKR-----QDKAIKVMHDFTEN 249

Mouse   251 -------TSVERMKENRMKEK-----EKQRVDFLQLMINSQNYKTKESHKALSDVEIVAQSVIFI 303
                   |.|...||...:|:     :|:|:..|.:::.|    |.:. ..|||.:|..:...|:
  Fly   250 IIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQS----TIDG-APLSDEDIREEVDTFM 309

Mouse   304 FAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAAL--PNKAPATYDTLLQMEYLDMVVNETLRL 366
            |.|::||:||:||.||.::.||:||::||.||...|  ..|:|.|...|.::::::.|:.|:|||
  Fly   310 FEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRL 374

Mouse   367 YPIAGRLERVCKTDVEINGLFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSKKNQDSINPYM 431
            :|....:.|....||||.|..||.||...:..|.|.:||:|:..|:|||||||. .:...|:||.
  Fly   375 HPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFD-ADVPQIHPYA 438

Mouse   432 YLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQP 467
            |:||.:|||||||.:||::.||..:.::|::|.:.|
  Fly   439 YIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLP 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a13	NP_031845.1	CYP3A	67..492	CDD:410743	132/431 (31%)
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	130/429 (30%)