Protein Alignment Cyp3a11 and Cyp6a8

DIOPT Version :9

• Sequence 1: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Sequence 2: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 517
• Identity: 164/517 - (31%)
• Similarity: 267/517 - (51%)
• Gaps: 50/517 - (9%)

Mouse    11 TWVLLAIS---LVLLYRYGTRKHELFKKQGIPGPKPLPFLGTV--LNYYKGLWKFDMECYKKYGK 70
            |::|..::   |.:|..|..||...||::|||...|....|.:  |...|.:.:...:.|.|:.:
  Fly     4 TYILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNKFRE 68

Mouse    71 T----WGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNRRDFGPVGIMSKAISISKDD------- 124
            :    .|.|..|:|...|.|.|..|.:|:|: ||.|:|:      ||...    .|||
  Fly    69 SKAPFVGFFFFQSPAAFVIDLELAKQILIKD-FSNFSNK------GIFYN----EKDDPISAHLF 122

Mouse   125 -----EWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKAKKGKPVTMKDVLGAYSMDVI 184
                 :|:..|..||.||||||:|.|:|.:....:..:..:.:|..|...:.::|::..:::|||
  Fly   123 NLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARFTVDVI 187

Mouse   185 TSTSFGVNVDSLNNPEDPFVEKAKKLLRFDFFDPLLFSVV-LFPFLTPVYEMLNICMFPKDSIEF 248
            .:.:||:..:||.:.:..|:...|:.|.......||...: .:|.|.....|:......:   ||
  Fly   188 GTCAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQ---EF 249

Mouse   249 FKKFVDRMKESRLDSKQKH--RVDFLQLMMNSHNNSKDKVSH----KALSDMEITAQSIIFIFAG 307
            :.:.|......|   :::|  |.||:.:::...|..:..:.:    :.|:..|:.||:.:|..||
  Fly   250 YSRIVTETVAVR---EKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAG 311

Mouse   308 YETTSSTLSFTLHSLATHPDIQKKLQDEIDEALPNKAPP-TYDTVMEMEYLDMVLNETLRLYPIA 371
            :||:|||:.|.|:.||.:||||.|::.|::|.:...... ||:...:::||:.||:||||||.|.
  Fly   312 FETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIV 376

Mouse   372 NRLERVCKKDVELNG---VYIPKGSTVMIPSYALHHDPQHWSEPEEFQPERFSKENKGSIDPYVY 433
            ..|:|:..|...:.|   ..|..|.:|:|||.|:||||..:.||.||:|||||.|.........:
  Fly   377 PNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSVAW 441

Mouse   434 LPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQPCKETQIPLKLS-RQGLLQPEKPIVLKV 494
            ||||:|||||:|:||..|..::.|..:::||.|..|.:|..||... :..:|..:..|.|||
  Fly   442 LPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYLKV 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a11	NP_031844.1	p450	39..494	CDD:278495	151/484 (31%)
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	150/480 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.720