Protein Alignment Cyp3a11 and Cyp6a20

DIOPT Version :10

• Sequence 1: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Sequence 2: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 515
• Identity: 167/515 - (32%)
• Similarity: 268/515 - (52%)
• Gaps: 54/515 - (10%)

Mouse    13 VLLAISLVLLYRYGTRKH-ELFKKQGIPGPKP-LPF------LGTVLNYYKGLWKFDMECYKKY- 68
            ::|.|.::....:...:| ..:|::|||..:| :|:      :.||  ::..::|   ..|.|.
  Fly     5 IVLLIGVITFVAWYVHQHFNYWKRRGIPHDEPKIPYGNTSELMKTV--HFADIFK---RTYNKLR 64

Mouse    69 GKTWGLFDG----QTPLLAVTDPETIKNVLVKECF------SVFTNRRDFGPVGIMSKAISISKD 123
            .||.|.|.|    ...::.|||.:..|.||::| |      .||.|.|| .|  :.:..::|. .
  Fly    65 NKTDGPFVGFYMYFKRMVVVTDIDFAKTVLIRE-FDKFHDRGVFHNERD-DP--LSANLVNID-G 124

Mouse   124 DEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKAK-KGKPVTMKDVLGAYSMDVITST 187
            .:||..|..|:|||||||:|.|||.|...||.|::...:.|. ....:.:.:|:..::.|||.|.
  Fly   125 QKWKTLRQKLTPTFTSGKMKTMFPTILTVGDELIRVFGETASADSDSMEITNVVARFTADVIGSC 189

Mouse   188 SFGVNVDSLNNPEDPFVEKAKKLL----RFDFFDPLLFSVVLFPFLTPVYEMLNICMFPKDSIEF 248
            :||::..||::|:..||:.....:    .....|.|||..   |.|.....|       |.:::.
  Fly   190 AFGLDCHSLSDPKAKFVQMGTTAITERRHGKSMDLLLFGA---PELAAKLRM-------KATVQE 244

Mouse   249 FKKFVDRMKESRLDSKQKHRV---DFLQLMMNSHNNSKDKVSHKALSDMEITAQSIIFIFAGYET 310
            .:.|...:....:|.:.|:.|   ||:.:::.......:......|:..||.||:.||..||:||
  Fly   245 VEDFYMNIIRDTVDYRVKNNVKRHDFVDMLIEMKLKFDNGDKENGLTFNEIAAQAFIFFLAGFET 309

Mouse   311 TSSTLSFTLHSLATHPDIQKKLQDEIDEAL-PNKAPPTYDTVMEMEYLDMVLNETLRLYPIANRL 374
            :|:|:.|.|:.||.|.|||.||:.||:..| .:.....||::.||.||:.|::||:|..|:...|
  Fly   310 SSTTMGFALYELACHQDIQDKLRTEINTVLKQHNGKLDYDSMREMTYLEKVIDETMRKRPVVGHL 374

Mouse   375 ERVCKKDVE-LNGVY-IPKGSTVMIPSYALHHDPQHWSEPEEFQPERFSKENKGSIDPYVYLPFG 437
            .||..:..: .|..| |.||:.|::|:.|:||||:.:.|||:|.||||.::.........:||||
  Fly   375 IRVATQHYQHTNPKYNIEKGTGVIVPTLAIHHDPEFYPEPEKFIPERFDEDQVQQRPACTFLPFG 439

Mouse   438 NGPRNCLGMRFALMNMKLALTKIMQNFSFQ--PCKETQIPLKLSRQG-LLQPEKPIVLKV 494
            :|||||:|:||..|.:.:.:..::.||.|:  |.| |.:||:..... ||..:..|.|||
  Fly   440 DGPRNCIGLRFGRMQVIVGMALLIHNFKFEFHPTK-TVVPLEYRTDDFLLSSKGGIHLKV 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a11	NP_031844.1	CYP3A	67..493	CDD:410743	151/450 (34%)
Cyp6a20	NP_611002.3	CYP6-like	67..495	CDD:410679	148/443 (33%)