Protein Alignment Cyp3a11 and Cyp6a19

DIOPT Version :9

• Sequence 1: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Sequence 2: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 517
• Identity: 150/517 - (29%)
• Similarity: 259/517 - (50%)
• Gaps: 73/517 - (14%)

Mouse     3 LVSALSLETWVLLAISLVLLYRYGTRKHELFKKQGIPGPKPLPFLGTVLNYYK-----GLWKFDM 62
            :|..|:|..|.:|            :.:..:|::|||...|...||.....::     |:.|
  Fly     8 VVGVLTLVAWWVL------------QNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILK--- 57

Mouse    63 ECYKKYGK-TWGLFDG----QTPLLAVTDPETIKNVLVKECF------SVFTNRRDFGPVGIMSK 116
            ..|.|:.| |.|.|.|    ....:.:||.:.:|.||::: |      .|:.|.:| .|   ::.
  Fly    58 RTYLKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRD-FDKFHDRGVYHNEKD-DP---LTN 117

Mouse   117 AISISKDDEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQK-AKKGKPVTMKDVLGAYS 180
            .::..:..:||..|..|:.||||.|:|.||..:...||.:::.:.:| :...:.:.:.|::..::
  Fly   118 NLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFT 182

Mouse   181 MDVITSTSFGVNVDSLNNPEDPFVEKAKKLLRFD----FFDPLLFSV------VLFPFLTPVYEM 235
            .|||...:||:..:||.:|:..||:.....||..    ..|.|:|.:      :.|.||.|
  Fly   183 SDVIGICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLP---- 243

Mouse   236 LNICMFPKDSIEFFKKFVDRMKESRLDSKQKHRV---DFLQLM--MNSHNNSKDKVSHKALSDME 295
                     |::   ||..::.:..:|.:.|.:|   ||:..:  |....:..||  ...|:..|
  Fly   244 ---------SVQ---KFYMKIVQDTIDYRMKRKVTRNDFMDTLIDMKQQYDKGDK--ENGLAFNE 294

Mouse   296 ITAQSIIFIFAGYETTSSTLSFTLHSLATHPDIQKKLQDEIDEALPN-KAPPTYDTVMEMEYLDM 359
            :.||:.:|..||:|..|:|:.|||:.||.:.|:|.||:.|||..|.. .....||::.::.|::.
  Fly   295 VAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEK 359

Mouse   360 VLNETLRLYPIANRLERVCKKDVELNG--VYIPKGSTVMIPSYALHHDPQHWSEPEEFQPERFSK 422
            |:||:||.:|:...|.|:..|..:.:.  .:|..|:.|::.:..:||||:.:.|||:|.||||.:
  Fly   360 VINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDE 424

Mouse   423 ENKGSIDPYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQPCKETQIPLKLSRQGLL 484
            |.........:||||.|||||:|:||..|.:.:.|..::.||.|:...:|.:|:|.:...||
  Fly   425 EQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYTINNLL 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a11	NP_031844.1	p450	39..494	CDD:278495	142/481 (30%)
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	142/481 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.720