Protein Alignment Cyp3a11 and Cyp6a13

DIOPT Version :10

• Sequence 1: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Sequence 2: NP_610390.1
• Gene: Cyp6a13 / 35837
• FlyBaseID: FBgn0033304
• Length: 493
• Species: Drosophila melanogaster
• Alignment Length: 513
• Identity: 169/513 - (32%)
• Similarity: 283/513 - (55%)
• Gaps: 57/513 - (11%)

Mouse    11 TWVLLAISLVLLYRYGTRKH-ELFKKQGIPGPKPLPFLGTVLNYYKGL-W-KFDMECYKKY---G 69
            |.::|..::.||.....|.| ..:.::|:.|.:|:.|.|.:....:.| | ..::..|:|:   .
  Fly     3 TLLVLVFTVGLLLYVKLRWHYSYWSRRGVAGERPVYFRGNMSGLGRDLHWTDINLRIYRKFRGVE 67

Mouse    70 KTWGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNRRDFGPVGIMSKAISISKDD---------- 124
            :..|.|...|..|.:.|.|.|::::::: ||.|.:|..|..|          :||
  Fly    68 RYCGYFTFMTKSLFIMDLELIRDIMIRD-FSSFADRGLFHNV----------RDDPLTGNLLFLD 121

Mouse   125 --EWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKAKKGKPVTMKDVLGAYSMDVITST 187
              ||:..|..|:..|||||:|.|||.:.:.|:.|.:..|.:..:   :..||:...::.|||.|.
  Fly   122 GPEWRWLRQNLTQVFTSGKMKFMFPNMVEVGEKLTQACRLQVGE---IEAKDLCARFTTDVIGSC 183

Mouse   188 SFGVNVDSLNNPEDPFVEKAKKLLRFDFFDPLLFSVVL--FPFLTP-VYEMLNICMFPKDSIEFF 249
            :||:..:||.:||..|....:.:.:    :| |.||::  |.|..| :...|...:|..:..||
  Fly   184 AFGLECNSLQDPESQFRRMGRSVTQ----EP-LHSVLVQAFMFAQPELARKLRFRLFRPEVSEF- 242

Mouse   250 KKFVDRMKESRLDSKQK---HRVDFLQLMMN-SHNNSKDKVSHKALSDMEITAQSIIFIFAGYET 310
              |:|.:::: ||.:::   ||.|.:||:|. .....||     |||..:|.||:::|..||::|
  Fly   243 --FLDTVRQT-LDYRRRENIHRNDLIQLLMELGEEGVKD-----ALSFEQIAAQALVFFLAGFDT 299

Mouse   311 TSSTLSFTLHSLATHPDIQKKLQDEIDEALP-NKAPPTYDTVMEMEYLDMVLNETLRLYPIANRL 374
            :|:|:||.|:.||.:||:|::|:.|:...|. |....|||:|.||.|||.|:.||||.|||...|
  Fly   300 SSTTMSFCLYELALNPDVQERLRVEVLAVLKRNNQKLTYDSVQEMPYLDQVVAETLRKYPILPHL 364

Mouse   375 ERVCKKDVEL--NGVYIPKGSTVMIPSYALHHDPQHWSEPEEFQPERFSKENKGSIDPYVYLPFG 437
            .|...|:.::  :.:.:..||.::||.:::||||:.:.:||:|.|.||..|...:..|:.|||||
  Fly   365 LRRSTKEYQIPNSNLILEPGSKIIIPVHSIHHDPELYPDPEKFDPSRFEPEEIKARHPFAYLPFG 429

Mouse   438 NGPRNCLGMRFALMNMKLALTKIMQNFSFQPCKETQIPLKL-SRQGLLQPEKPIVLKV 494
            .|||||:|.||..:.:|:.|..::::|.|...::||||||. ||..|:..::.:.|::
  Fly   430 EGPRNCIGERFGKLQVKVGLVYLLRDFKFSRSEKTQIPLKFSSRNFLISTQEGVHLRM 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a11	NP_031844.1	CYP3A	67..493	CDD:410743	154/451 (34%)
Cyp6a13	NP_610390.1	CYP6-like	67..484	CDD:410679	153/444 (34%)