Protein Alignment Cyp3a11 and Cyp9b2

DIOPT Version :10

• Sequence 1: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Sequence 2: NP_523646.1
• Gene: Cyp9b2 / 35635
• FlyBaseID: FBgn0015039
• Length: 505
• Species: Drosophila melanogaster
• Alignment Length: 520
• Identity: 173/520 - (33%)
• Similarity: 281/520 - (54%)
• Gaps: 50/520 - (9%)

Mouse     9 LETWVLLAISLVLLYRYGTRKHELFKKQGIPGPKPLPFLGTVL-------NYYKGLWKFDMECYK 66
            :|..:.|.:...|:|::.|...:.|:::.:...||.||:|.:.       ::.:.|.:|    |:
  Fly     4 IEICLALVVIGYLIYKWSTATFKTFEERKLYFEKPYPFVGNMAAAALQKSSFQRQLTEF----YE 64

Mouse    67 --KYGKTWGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNRRDF--GPVGIMSKAISISKDDEWK 127
              :..|..|.|:.:||::.:.|||.||.|.||: |..|.|.:.|  ....:.:..:|:.:|..||
  Fly    65 RTRQHKLVGFFNMRTPMITLNDPELIKKVCVKD-FDHFPNHQPFITSNDRLFNDMLSVMRDQRWK 128

Mouse   128 RYRALLSPTFTSGKLKEMFPVI-EQYGDILVKYLRQKAK-----KGKPVTMKDVLGAYSMDVITS 186
            ..|..|:|.||:.|::.||.:: |.:.:.| ::|...:|     ||..|.||.:....|.|:|.:
  Fly   129 HMRNTLTPVFTAAKMRNMFTLMNESFAECL-QHLDSSSKTLPGRKGFEVDMKVMCNKLSNDIIAT 192

Mouse   187 TSFGVNVDSLNNPEDPFVEKAKKLLRFDFFDPLLFSVVLFPFLTP-VYEMLNICMFPKDSIEFFK 250
            |:||:.|:|.:||::.|.|..:.|:   |...|.|...:...|.| ::.:|.:.:|....:::|.
  Fly   193 TAFGLKVNSYDNPKNEFYEIGQSLV---FSRGLQFFKFMLSTLVPKLFSLLKLTIFDSAKVDYFA 254

Mouse   251 KFVDRMKESRLDSKQKH---RVDFLQLMMNSHNNSKDKVSHKALSDMEITAQSIIFIFAGYETTS 312
            :.|....:.|    :||   |.|.:||:|.:.|.|:||     .:|.||.||..||.||.:|..|
  Fly   255 RLVVEAMQYR----EKHNITRPDMIQLLMEAKNESEDK-----WTDDEIVAQCFIFFFAAFENNS 310

Mouse   313 STLSFTLHSLATHPDIQKKLQDEIDE---ALPNKAPPTYDTVMEMEYLDMVLNETLRLYPIANRL 374
            :.:..|.:.|..:||:|::|.:||.|   || |.||.|||.|.:|.|:|||::|:||.:.:|...
  Fly   311 NLICTTTYELLYNPDVQERLYEEIVETKKAL-NGAPLTYDAVQKMTYMDMVISESLRKWTLAAAT 374

Mouse   375 ERVCKKDVEL---NGVYI---PKGSTVMIPSYALHHDPQHWSEPEEFQPERFSKENKGSIDPYVY 433
            :|:|.||..|   :|..:   ..|..:.||...||.|.:::.||.:|.|:|||:|.||.:.||.|
  Fly   375 DRLCSKDYTLTDDDGTKLFDFKVGDRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVPYTY 439

Mouse   434 LPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQPCKETQIPLKLSRQGL-LQPEKPIVLKVVPR 497
            ||||.|||||:|.|:|||.:|..|..::.::..:....|...|..|..|. ..|.....:.:|||
  Fly   440 LPFGVGPRNCIGNRYALMQVKGMLFNLLLHYKIEASPRTIKDLWGSASGFNFTPRSGFWMHLVPR 504

Mouse   498  497
              Fly   505  504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a11	NP_031844.1	CYP3A	67..493	CDD:410743	156/447 (35%)
Cyp9b2	NP_523646.1	CYP6-like	67..498	CDD:410679	156/445 (35%)