Protein Alignment Cyp3a11 and Cyp6t1

DIOPT Version :9

• Sequence 1: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Sequence 2: NP_608457.1
• Gene: Cyp6t1 / 33127
• FlyBaseID: FBgn0031182
• Length: 529
• Species: Drosophila melanogaster
• Alignment Length: 494
• Identity: 145/494 - (29%)
• Similarity: 243/494 - (49%)
• Gaps: 56/494 - (11%)

Mouse    14 LLAISLVLLYRYGTRKHELFKKQGIPGPKPLPFLGTVLNYYKGLWKFD---MECYKKYGKTWGLF 75
            ||.:::|.|::.....|  :::.|:|.....||:|.|.|..:|...|.   .|.|:........|
  Fly    29 LLVVTIVWLWQILHFWH--WRRLGVPFVPAAPFVGNVWNLLRGACCFGDQFRELYESKEAAGRAF 91

Mouse    76 DGQTPL----LAVTDPETIKNVLVKECFSVFTNRRD-----FGPVGIMSKAISISKDDEWKRYRA 131
            .|...|    |.:.||..||.::|:: |:.|::|.:     ...:|  |:.:..||.:.|:....
  Fly    92 VGIDVLHNHALLLRDPALIKRIMVED-FAQFSSRFETTDPTCDTMG--SQNLFFSKYETWRETHK 153

Mouse   132 LLSPTFTSGKLKEMFPVIEQYGDILVKYLRQK--AKKGKPVTMKDVLGAYSMDVITSTSFGVNVD 194
            :.:|.|.:||::.|:.::|..|..|.:::.||  .:....:.:|.:...::.|:|.|.:||:...
  Fly   154 IFAPFFAAGKVRNMYGLLENIGQKLEEHMEQKLSGRDSMELEVKQLCALFTTDIIASLAFGIEAH 218

Mouse   195 SLNNPEDPF----VE----KAKKLLRFDFFDPLLFSVVLFPFLTPVYEMLNICMFPKDSIEFFKK 251
            ||.|||..|    :|    :.|:||.       ||::..||.|:   ..:...::.::...|.:|
  Fly   219 SLQNPEAEFRRMCIEVNDPRPKRLLH-------LFTMFFFPRLS---HRVGTHLYSEEYERFMRK 273

Mouse   252 FVDRMKESRLDSKQKHR--VD-FLQLMMNSHNNSKDKVSHKALSDMEITAQSIIFIFAGYETTSS 313
            .:|.:...|.:|.:...  :| ||||   ......:.:.|:  .|. ..||:...:.||::|:||
  Fly   274 SMDYVLSQRAESGENRHDLIDIFLQL---KRTEPAESIIHR--PDF-FAAQAAFLLLAGFDTSSS 332

Mouse   314 TLSFTLHSLATHPDIQKKLQDEIDEALPNKAPP--TYDTVMEMEYLDMVLNETLRLYPIANRLER 376
            |::|.|:.||.:..||.:|:.|:..||.:....  :.|||..:.||..|::|.|||||....|:|
  Fly   333 TITFALYELAKNTTIQDRLRTELRAALQSSQDRQLSCDTVTGLVYLRQVVDEVLRLYPPTAFLDR 397

Mouse   377 VCKK----DVE-LNG---VYIPKGSTVMIPSYALHHDPQHWSEPEEFQPERFSKENKGSIDPYVY 433
            .|..    |:. .||   ..:..|:.|.|....:|.|.|:|..||.|.|||||.|.:....|..|
  Fly   398 CCNSRTGYDLSPWNGGSPFKLRAGTPVYISVLGIHRDAQYWPNPEVFDPERFSAEQRQQHHPMTY 462

Mouse   434 LPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQPCKET 472
            ||||.|||.|:|.....:.:|:.|..|:.:|..:.|:.|
  Fly   463 LPFGAGPRGCIGTLLGQLEIKVGLLHILNHFRVEVCERT 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a11	NP_031844.1	p450	39..494	CDD:278495	139/469 (30%)
Cyp6t1	NP_608457.1	p450	91..515	CDD:299894	129/430 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820