DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp2g1 and spo

DIOPT Version :9

Sequence 1:	NP_038837.1	Gene:	Cyp2g1 / 13108	MGIID:	109612	Length:	494	Species:	Mus musculus
Sequence 2:	NP_001286943.1	Gene:	spo / 38631	FlyBaseID:	FBgn0003486	Length:	543	Species:	Drosophila melanogaster

Alignment Length:	501	Identity:	140/501 - (27%)
Similarity:	214/501 - (42%)	Gaps:	93/501 - (18%)

- Green bases have known domain annotations that are detailed below.

Mouse    35 PGPTPIPFLGN--FLQVRTDATFQSFQKLQKKYGSVFTVYFGPRPVVVLCGHEAVKEALVDQADD 97
            |||.|.|.:||  .|....|:.|..|..|.::||.::::.||....:|:...|.::|.|......
  Fly    56 PGPRPWPIIGNLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKV 120

Mouse    98 FSGRGEMPTLEKNFQG---YGLALSNGERWKIL--------------RRFSLTVLRNFGMGKRSI 145
            .|||.:.....|.|.|   ..|||.:   |..|              |.||...::...:|...:
  Fly   121 MSGRPDFIRYHKLFGGERSNSLALCD---WSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEM 182

Mouse   146 EERIQEEAGYLLEELHKVKGAPIDPTLYLSRTVSNVICSVVFGKRFDYQDQRFQSLMRMINESFV 210
            |...:|....|      |.|.||:....:.:..:|:....:...||||.|..||.:::..:|.|.
  Fly   183 EHWNRELGNQL------VPGEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQYFDEIFW 241

Mouse   211 EMSK-------PWAQLYDMYWKVMQYFPGRH-NYLYNLIEDLKDFIASR-VKINEASFDPSNP-R 265
            |:::       ||  ||..|        .|| |.:.|....::.||..| ::..|.|.|...| |
  Fly   242 EINQGHPLDFLPW--LYPFY--------QRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDR 296

Mouse   266 DFIDCFLIKMHQDKSDPHTEFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLLLKYPEVEAKIHEE 330
            ||.|..|..:.:||...      :|.::..|..|..|...|.:.:......:.|..::..:|.||
  Fly   297 DFTDALLKSLLEDKDVS------RNTIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEE 355

Mouse   331 INQVI-GTHRTPRVDDRAKMPYTDAVIHEIQRLTDIVPLGVPHNVTRDTHFRGYLLPKGTDVYPL 394
            |:.:| ..:|:..:.|...||||.|.|.|:.|.:. .|: |||..|.||...||.:.|||.|: :
  Fly   356 IDAIIEEENRSINLLDMNAMPYTMATIFEVLRYSS-SPI-VPHVATEDTVISGYGVTKGTIVF-I 417

Mouse   395 FGSVLK-DPKYFRYPDAFYPQHFLD---------------------EQGRFKKN-DAFVVFSSGK 436
            ...||. ..|::..|..|.|..||:                     |:.:.|:| ..|:.||.||
  Fly   418 NNYVLNTSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIGK 482

Mouse   437 RICVGEALARMELFLYFTSILQRFSL------------RSLVPPAD 470
            |.|:|:.|.|...||...:::||:::            .||..|||
  Fly   483 RTCIGQNLVRGFGFLVVVNVMQRYNISSHNPSTIKISPESLALPAD 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp2g1	NP_038837.1	p450	34..491	CDD:278495	140/501 (28%)
spo	NP_001286943.1	p450	56..540	CDD:299894	140/501 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010