Protein Alignment ADH7 and Fdh

DIOPT Version :10

• Sequence 1: NP_001159976.1
• Gene: ADH7 / 131
• HGNCID: 256
• Length: 394
• Species: Homo sapiens
• Sequence 2: NP_524310.1
• Gene: Fdh / 41311
• FlyBaseID: FBgn0011768
• Length: 379
• Species: Drosophila melanogaster
• Alignment Length: 377
• Identity: 197/377 - (52%)
• Similarity: 258/377 - (68%)
• Gaps: 4/377 - (1%)

Human    22 SVEAGVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGT-MVSKFPVI 85
            :.|..||.|||||.||.|:|..||:|||||||..||||||.|||:|.||...:.|. ....|||:
  Fly     3 ATEGKVITCKAAVAWEAKKPLVIEDIEVAPPKAHEVRIKITATGVCHTDAFTLSGADPEGLFPVV 67

Human    86 VGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDIT-GRGVLADGTTR 149
            :|||..|||||:|||||..|.||.||.|::|||.||..|::...|||.:..:| |.||:.:||:|
  Fly    68 LGHEGAGIVESVGEGVTNFKAGDHVIALYIPQCNECKFCKSGKTNLCQKIRLTQGAGVMPEGTSR 132

Human   150 FTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGST 214
            .:|||:.:.|||.||||.|||||.:.|:.||::.||.|||||:|||.|||||||:.|.||:.|||
  Fly   133 LSCKGQQLFHFMGTSTFAEYTVVADISLTKINEKAPLEKVCLLGCGISTGYGAALNTAKVEAGST 197

Human   215 CVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKD--STKPISEVLSEM 277
            |.|:|||.|||:|.:|||.|||.:|.|||:|.||||.|...|.|:.::|||  ....|...|.::
  Fly   198 CAVWGLGAVGLAVGLGCKKAGAGKIYGIDINPDKFELAKKFGFTDFVNPKDVADKGSIQNYLIDL 262

Human   278 TGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGL 342
            |.....||||.||::.||..||.:.|..:|||||:||..:.:.::..|..|..||.|||..|||.
  Fly   263 TDGGFDYTFECIGNVNTMRSALEATHKGWGTSVVIGVAGAGQEISTRPFQLVVGRVWKGSAFGGW 327

Human   343 KSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVLTF 394
            :|..||||||.::|.|...:|:.|||.||..:|:|.|:|::.|:|||:::.:
  Fly   328 RSVSDVPKLVEDYLKKDLLVDEFITHELPLSQINEAFDLMHKGESIRSIIKY 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ADH7	NP_001159976.1	alcohol_DH_class_I_II_IV	27..394	CDD:176259	196/370 (53%)
Fdh	NP_524310.1	alcohol_DH_class_III	9..378	CDD:176260	195/368 (53%)