Protein Alignment ADH7 and Drat

DIOPT Version :10

• Sequence 1: NP_001159976.1
• Gene: ADH7 / 131
• HGNCID: 256
• Length: 394
• Species: Homo sapiens
• Sequence 2: NP_610293.3
• Gene: Drat / 35687
• FlyBaseID: FBgn0033188
• Length: 434
• Species: Drosophila melanogaster
• Alignment Length: 325
• Identity: 67/325 - (20%)
• Similarity: 106/325 - (32%)
• Gaps: 115/325 - (35%)

Human    58 RIKILATGIC-RTDDHVIKGTMVSK----------------------------FPVIVGHEATGI 93
            ||:|:..|.| |..|.....|.:|.                            ||   |.|..|:
  Fly    90 RIRIVCAGACYRRRDRANSITSMSSVSSELSDYCPSVNSMSSPAHQGIREGSFFP---GFEVAGV 151

Human    94 VESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVH 158
            :||:|..:|                 |.|       |..:|   .|:.|:             |:
  Fly   152 IESLGSEIT-----------------EAN-------NRGLR---IGQRVI-------------VY 176

Human   159 HFMNT-STFTEYTVV-DESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKV------------ 209
            .|..| :.:.|..|| |...|..|.|:.|.|...::..|....:.|..|...|
  Fly   177 PFDETPAGYAELLVVPDLKHVVPIPDSLPMEVAAMLPTGALLAWNAVFKAQAVVTQILSQRAATE 241

Human   210 ---KPGSTCVVFGLGGVGLSVIMGCK----SAGASRI-IGIDLNKD-------KFEKAMAVGATE 259
               ||  ..::.|.||:.|..:....    :.||..: |.:...:|       :.:....|...|
  Fly   242 PKRKP--KILIVGTGGLALWAVRIASYHFATTGADNVDITVASLRDEGFRLATEIKNVSVVQWNE 304

Human   260 CI-SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDAL-ASCH-MNYGTSVVVGVPPSAKML 321
            |: .|:         |.|.|.:..|...:|:....|...:| .|.| ::.|..|::....:.|:|
  Fly   305 CLYEPQ---------LIERTKDVCGGAVDVVIDFGTTSRSLHRSMHCLSKGGVVLISDEVAEKLL 360

Human   322  321
              Fly   361  360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ADH7	NP_001159976.1	alcohol_DH_class_I_II_IV	27..394	CDD:176259	67/325 (21%)
Drat	NP_610293.3	MDR	144..428	CDD:450120	57/271 (21%)