DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp2c29 and spo

DIOPT Version :9

Sequence 1:	NP_031841.3	Gene:	Cyp2c29 / 13095	MGIID:	103238	Length:	490	Species:	Mus musculus
Sequence 2:	NP_001286943.1	Gene:	spo / 38631	FlyBaseID:	FBgn0003486	Length:	543	Species:	Drosophila melanogaster

Alignment Length:	514	Identity:	144/514 - (28%)
Similarity:	230/514 - (44%)	Gaps:	91/514 - (17%)

- Green bases have known domain annotations that are detailed below.

Mouse    31 PGPTPLPIIGNFLQIDVKNIS--QSFTNFSKAYGPVFTLYLGSKPTVILHGYEAVKEALIDRGEE 93
            |||.|.|||||...:|....|  ..||..::.||.:::|..|....::::..|.::|.|...|:.
  Fly    56 PGPRPWPIIGNLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKV 120

Mouse    94 FAGRGSFPMAEKIIKGFGVVFSNGNR---WKEM--------------RRFTLMTLRNLGMGKRNI 141
            .:||..|....|:   ||...||...   |.::              |.|:...::...:|...:
  Fly   121 MSGRPDFIRYHKL---FGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEM 182

Mouse   142 EDRVQEEAQCLVEELRKTKGSPCD--PTFILSCAPCNVICSIIFQNRFDYKDKEFLILMD----- 199
            |...:|....||      .|.|.:  |..:.:||  |:....:...||||.|.:|..::.
  Fly   183 EHWNRELGNQLV------PGEPINIKPLILKACA--NMFSQYMCSLRFDYDDVDFQQIVQYFDEI 239

Mouse   200 --KINENVKILSSPWLQVCNSFPSLIDYCPGSHHKIVKNFNYLKSYLLEKIKEHKE-SLDVTNP- 260
              :||:...:...|||     :|    :.....:||:...:.::.:::|:|..|:| |:|:..|
  Fly   240 FWEINQGHPLDFLPWL-----YP----FYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPD 295

Mouse   261 RDFIDYYLIKQKQVNHIEQSEFSLENLASTINDLFGAGTETTSTTLRYALLLLLKYPDVTAKVQE 325
            |||.| .|:|    :.:|..:.|...:...:.|..| |.......:...|..:.|..|:..::||
  Fly   296 RDFTD-ALLK----SLLEDKDVSRNTIIFMLEDFIG-GHSAVGNLVMLVLAYIAKNVDIGRRIQE 354

Mouse   326 EIDRVV-GRHRSPCMQDRSHMPYTDAMIHEVQRFIDLLPTSLPHAVTCDIKFRKYLIPKGTTVIT 389
            |||.:: ..:||..:.|.:.||||.|.|.||.|:..  ...:||..|.|.....|.:.|||.|..
  Fly   355 EIDAIIEEENRSINLLDMNAMPYTMATIFEVLRYSS--SPIVPHVATEDTVISGYGVTKGTIVFI 417

Mouse   390 SLSSVLHDSKEF-PNPEMFDPGHFLNGN-----GNFKKSD-----------------YFMPFSTG 431
            : :.||:.|::| .||:.|:|..||..:     .|.|.||                 :|:|||.|
  Fly   418 N-NYVLNTSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIG 481

Mouse   432 KRICAGEGLARMELFLILTTILQNFKLKSLVHPKEIDITPVMNGFASLPPPYQLCFIPL 490
            ||.|.|:.|.|...||::..::|.:.:.| .:|..|.|:|     .||..|.. || ||
  Fly   482 KRTCIGQNLVRGFGFLVVVNVMQRYNISS-HNPSTIKISP-----ESLALPAD-CF-PL 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp2c29	NP_031841.3	p450	30..487	CDD:278495	140/509 (28%)
spo	NP_001286943.1	p450	56..540	CDD:299894	144/514 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920