Protein Alignment Cyp2a12 and spo

DIOPT Version :9

• Sequence 1: NP_598418.1
• Gene: Cyp2a12 / 13085
• MGIID: 105055
• Length: 492
• Species: Mus musculus
• Sequence 2: NP_001286943.1
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Alignment Length: 516
• Identity: 138/516 - (26%)
• Similarity: 234/516 - (45%)
• Gaps: 85/516 - (16%)

Mouse     7 LLLAILAFLSVMVLVSVWQ---QKIRGK--------------LPPGPIPLPFIGN--YLQLNRKD 52
            :||::||...:.::..|.:   |.::.|              ..|||.|.|.|||  .|...|..
  Fly    12 ILLSVLATSYICIIYGVKRRVLQPVKTKNSTEINHNAYQKYTQAPGPRPWPIIGNLHLLDRYRDS 76

Mouse    53 VYSSITQLQEHYGPVFTIHLGPRRVVVLYGYDAVKEALVDHAEEFSGRGEQATFNTLFKG---YG 114
            .::..|.|.:.||.::::..|..|.:|:...:.::|.|..:.:..|||.:...::.||.|   ..
  Fly    77 PFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSGRPDFIRYHKLFGGERSNS 141

Mouse   115 VAFSNGERAKQLRRFSIATLRDFGMGKRGVEERIQEEAGCL-IKMLQGTC--------------- 163
            :|..:..:.:|.||         .:.:|....|   |..|. :||.|..|
  Fly   142 LALCDWSQLQQKRR---------NLARRHCSPR---EFSCFYMKMSQIGCEEMEHWNRELGNQLV 194

Mouse   164 -GAPIDPTIYLSKTASNVISSIVFGDRFNYEDKEFLSLLQMMGQVNKFAASPTGQLYDMFHSVMK 227
             |.||:....:.|..:|:.|..:...||:|:|.:|..::|...::  |.....|...|....:..
  Fly   195 PGEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQYFDEI--FWEINQGHPLDFLPWLYP 257

Mouse   228 YLPGPQQQIIKDSHKLEDFMIQK-VKQNQSTLDPNSP-RDFIDSFLIHMQKEKYVNSEFHMKNLV 290
            :......:||..|..:..|:::: ::..:.::|.:.| |||.|:.|..:.::|.|:     :|.:
  Fly   258 FYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDRDFTDALLKSLLEDKDVS-----RNTI 317

Mouse   291 MTSLNLFFAGSETVSSTLRYGFLLLMKHPDVEAKVHEEIDRVI-GRNRQPQYEDHMKMPYTQAVI 354
            :..|..|..|...|.:.:......:.|:.|:..::.||||.:| ..||.....|...||||.|.|
  Fly   318 IFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEEIDAIIEEENRSINLLDMNAMPYTMATI 382

Mouse   355 NEIQRFSNFAPLGIPRRITKDTSFRGFFLPKGTEVFPILGSLMTDPKFFSSPKDFNPQHFLD--- 416
            .|:.|:|: :|: :|...|:||...|:.:.|||.||.....|.|..||:.:||:|||..||:
  Fly   383 FEVLRYSS-SPI-VPHVATEDTVISGYGVTKGTIVFINNYVLNTSEKFWVNPKEFNPLRFLEPSK 445

Mouse   417 ------------------DKGQLKK-IPAFLPFSTGKRFCLGDSLAKMELFLFFTTILQNF 458
                              :|.|||: ||.|||||.|||.|:|.:|.:...||....::|.:
  Fly   446 EQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIGKRTCIGQNLVRGFGFLVVVNVMQRY 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp2a12	NP_598418.1	p450	33..489	CDD:278495	131/473 (28%)
spo	NP_001286943.1	p450	56..540	CDD:299894	131/472 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920