Protein Alignment Cyp2a12 and spo

DIOPT Version :10

• Sequence 1: NP_598418.1
• Gene: Cyp2a12 / 13085
• MGIID: 105055
• Length: 492
• Species: Mus musculus
• Sequence 2: NP_647975.2
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Alignment Length: 516
• Identity: 138/516 - (26%)
• Similarity: 234/516 - (45%)
• Gaps: 85/516 - (16%)

Mouse     7 LLLAILAFLSVMVLVSVWQ---QKIRGK--------------LPPGPIPLPFIGN--YLQLNRKD 52
            :||::||...:.::..|.:   |.::.|              ..|||.|.|.|||  .|...|..
  Fly    12 ILLSVLATSYICIIYGVKRRVLQPVKTKNSTEINHNAYQKYTQAPGPRPWPIIGNLHLLDRYRDS 76

Mouse    53 VYSSITQLQEHYGPVFTIHLGPRRVVVLYGYDAVKEALVDHAEEFSGRGEQATFNTLFKG---YG 114
            .::..|.|.:.||.::::..|..|.:|:...:.::|.|..:.:..|||.:...::.||.|   ..
  Fly    77 PFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSGRPDFIRYHKLFGGERSNS 141

Mouse   115 VAFSNGERAKQLRRFSIATLRDFGMGKRGVEERIQEEAGCL-IKMLQGTC--------------- 163
            :|..:..:.:|.||         .:.:|....|   |..|. :||.|..|
  Fly   142 LALCDWSQLQQKRR---------NLARRHCSPR---EFSCFYMKMSQIGCEEMEHWNRELGNQLV 194

Mouse   164 -GAPIDPTIYLSKTASNVISSIVFGDRFNYEDKEFLSLLQMMGQVNKFAASPTGQLYDMFHSVMK 227
             |.||:....:.|..:|:.|..:...||:|:|.:|..::|...::  |.....|...|....:..
  Fly   195 PGEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQYFDEI--FWEINQGHPLDFLPWLYP 257

Mouse   228 YLPGPQQQIIKDSHKLEDFMIQK-VKQNQSTLDPNSP-RDFIDSFLIHMQKEKYVNSEFHMKNLV 290
            :......:||..|..:..|:::: ::..:.::|.:.| |||.|:.|..:.::|.|:     :|.:
  Fly   258 FYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDRDFTDALLKSLLEDKDVS-----RNTI 317

Mouse   291 MTSLNLFFAGSETVSSTLRYGFLLLMKHPDVEAKVHEEIDRVI-GRNRQPQYEDHMKMPYTQAVI 354
            :..|..|..|...|.:.:......:.|:.|:..::.||||.:| ..||.....|...||||.|.|
  Fly   318 IFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEEIDAIIEEENRSINLLDMNAMPYTMATI 382

Mouse   355 NEIQRFSNFAPLGIPRRITKDTSFRGFFLPKGTEVFPILGSLMTDPKFFSSPKDFNPQHFLD--- 416
            .|:.|:|: :|: :|...|:||...|:.:.|||.||.....|.|..||:.:||:|||..||:
  Fly   383 FEVLRYSS-SPI-VPHVATEDTVISGYGVTKGTIVFINNYVLNTSEKFWVNPKEFNPLRFLEPSK 445

Mouse   417 ------------------DKGQLKK-IPAFLPFSTGKRFCLGDSLAKMELFLFFTTILQNF 458
                              :|.|||: ||.|||||.|||.|:|.:|.:...||....::|.:
  Fly   446 EQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIGKRTCIGQNLVRGFGFLVVVNVMQRY 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp2a12	NP_598418.1	CYP2A	64..487	CDD:410761	119/440 (27%)
spo	NP_647975.2	CYP1_2-like	89..520	CDD:410710	118/439 (27%)