Protein Alignment Cyp26a1 and Cyp313a1

DIOPT Version :10

• Sequence 1: NP_031837.2
• Gene: Cyp26a1 / 13082
• MGIID: 1096359
• Length: 497
• Species: Mus musculus
• Sequence 2: NP_650368.1
• Gene: Cyp313a1 / 41759
• FlyBaseID: FBgn0038236
• Length: 492
• Species: Drosophila melanogaster
• Alignment Length: 508
• Identity: 125/508 - (24%)
• Similarity: 222/508 - (43%)
• Gaps: 54/508 - (10%)

Mouse    15 VLPLLLFLAALKLWDLYCVSSRDRSCALPLP-PGTMGFPFFGETLQMVLQRRKFLQMKRR---KY 75
            :|.:.|.||...|:.:|.:.||.|...|.|. ||.:|.|..|.:|:.::..::.|..:.:   ||
  Fly     1 MLTINLLLAVGALFWIYFLWSRRRLYFLMLKIPGPIGLPILGSSLENIITYKRKLSFRTKYLNKY 65

Mouse    76 GFIYKTHLFGRPTVRVMGADNVRRILLGE--HRLVSVHWPASVRTILGAGCLSNLHDSSHKQRKK 138
            |....|.:...|.:.......|..|....  |. .|.|...::.:.:|.|.|.. .|.....|:|
  Fly    66 GSTILTWMGPVPFIVTRDPKVVEDIFSSPDCHN-KSQHIVNAITSCMGNGLLGK-QDPHWLDRRK 128

Mouse   139 VIMQAFSREALQCYVPVIAEE---VSSCLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPGP 200
            ....:|.::.|..:..:...|   :.:.|:.::..||  :.|.||:.|..|:||.:..:|.|.
  Fly   129 HFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKGE--IDVVPEMLRWSFKIAAQTTMGSEV-- 189

Mouse   201 AGGGEDEQ----QLVEAFEEM----TRNLFSLPI--DVPFSGL--YRGVKARNL--IHARIEENI 251
               ..||.    .|||:||.:    |.|:. :|:  :...|.:  |..::|.|.  |...::..:
  Fly   190 ---KHDEHFKNGSLVESFESLISHSTLNIL-MPLVQNRMISKICGYDKLRADNFSRIQKMLDNVV 250

Mouse   252 RAKIRRLQATEPDGGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYL 316
            ..|:..|..|:.|......:...:| .:.:|: :....:|.....::..|::|:|......:..|
  Fly   251 NKKVNPLPKTDSDPESNIVINRAME-LYRKGD-ITYMDVKSECCIMIAAGYDTSALTVYHALFLL 313

Mouse   317 GLYPHVLQKVREEIKSKGLLCKSNQDNKLDMETLEQLKYTGCVIKETLRLNPPVPGGFRVALKTF 381
            ..:|...:.|.||:  .|:...:.... :....:::|.|...||||||||.|.:|...|......
  Fly   314 ANHPEHQEAVFEEL--NGVFPDAGHFG-ITYPDMQKLDYLERVIKETLRLIPAIPITARETKNDV 375

Mouse   382 EL-NGYQIPKGWNVIYSICDTHDVADIF-TNKEEFNPDRFIVPHPEDASRFSFIPFGGGLRSCVG 444
            .| ||..||||..:...:..||...::: .:.:.||||.|:..:.|....:::|||..|.|:|:|
  Fly   376 RLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNFLAENMEQKHPYAYIPFARGKRNCIG 440

Mouse   445 KEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYP----VDNLPARFTHF 493
            .::|.:..|.....:.|:.         .:.|| |:|.    |||:..:...:
  Fly   441 SKYAMMSSKFALCRILRNY---------KISTS-TLYKDLVYVDNMTMKLAEY 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp26a1	NP_031837.2	CYP26A1	55..490	CDD:410731	110/462 (24%)
Cyp313a1	NP_650368.1	CYP313-like	66..487	CDD:410680	105/443 (24%)