Protein Alignment Cyp26a1 and Cyp4e2

DIOPT Version :9

• Sequence 1: NP_031837.2
• Gene: Cyp26a1 / 13082
• MGIID: 1096359
• Length: 497
• Species: Mus musculus
• Sequence 2: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 476
• Identity: 111/476 - (23%)
• Similarity: 191/476 - (40%)
• Gaps: 63/476 - (13%)

Mouse    16 LPLLLFLAALKLWDLYCVSSRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMK---RRKYG- 76
            ||||| :|.|:|      |:..|...|....|..|.|..|...||.....:.|...   ..:||
  Fly    11 LPLLL-VAYLEL------STFRRRRVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSWWHQYGK 68

Mouse    77 --FIYKTHLFGRPTVRVMGADNVRRILLGEHRLVS-------VH-WPASVRTILGAGCLSNLHDS 131
              |::....:....|.   :......:|....|::       .| |       ||.|.|::....
  Fly    69 DNFVFWIGTYSNVLVT---SSKYLEFILSSQTLITKSDIYQLTHPW-------LGLGLLTSTGSK 123

Mouse   132 SHKQRKKVIMQAFSREALQCYVPVIAEEVSSCLE--QWLSCGERGLLVYPEVKRLMFRIAMRILL 194
            .||.| |:|..||....||.:..|:.|..:..::  :.::.|:.......:...|...:.....:
  Fly   124 WHKHR-KMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAM 187

Mouse   195 GCEPGPAGGGED-EQQLVEAFEEMTRN--------------LFSLPIDVP-FSGLYRGVK--ARN 241
            |..   ....|: ...:|:||::|..|              |:.|..|.| :|...:.::  ...
  Fly   188 GVS---INAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNE 249

Mouse   242 LIHARIEENIRAKIRRLQATEPDGGCKDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTA 306
            :|..|||.:....:......|........|..|:..:.: |..|:.:.|.:..:..:|.||:||.
  Fly   250 IIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTID-GRPLNSKELYEEVSTFMFEGHDTTT 313

Mouse   307 SAATSLITYLGLYPHVLQKVREEIKSKGLLCKSNQDNKLDMETLEQLKYTGCVIKETLRLNPPVP 371
            |..:..:..|..:....:|:.:|  .:.::..|........:.:.|:||....|||..|:.|.||
  Fly   314 SGVSFAVYLLSRHQDEQRKLFKE--QREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVP 376

Mouse   372 GGFRVALKTFELNGYQIPKGWNVIYSICDTHDVADIFTNKEEFNPDRFIVPHPEDASRFSFIPFG 436
            ...|...|.:.::|..:|||..:...:........:|.:..:|.|:||.:..|   ..|.::||.
  Fly   377 FIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKP---GPFEYVPFS 438

Mouse   437 GGLRSCVGKEFAKILLKIFTV 457
            .|.|:|:|::||  ||:|.||
  Fly   439 AGPRNCIGQKFA--LLEIKTV 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp26a1	NP_031837.2	p450	43..491	CDD:299894	100/449 (22%)
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	100/445 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910