Protein Alignment Cyp26a1 and Cyp4ac1

DIOPT Version :10

• Sequence 1: NP_031837.2
• Gene: Cyp26a1 / 13082
• MGIID: 1096359
• Length: 497
• Species: Mus musculus
• Sequence 2: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 503
• Identity: 121/503 - (24%)
• Similarity: 217/503 - (43%)
• Gaps: 75/503 - (14%)

Mouse     1 MGLPALLASALCTFVLPLLL-------FLAALKLWDLYCVSSRDRS---CALPLPPGTMGFPFFG 55
            :|:|.|||      ||.|||       |:.:|    ...|.:.|.|   ..:.:.||...   ||
  Fly     6 LGIPILLA------VLTLLLKHINKTYFILSL----TKRVRTEDGSPLESKVAIMPGKTR---FG 57

Mouse    56 ETLQMV---------LQRRKFLQMKRRKY--GFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVS 109
            ..|.::         ..|....:.|.:.|  .|:|      .|...|:..:....:......:..
  Fly    58 NNLDILNFTPASVFNFVRESTAKAKGQNYLWYFLY------APMYNVVRPEEAEEVFQSTKLITK 116

Mouse   110 VHWPASVRTILGAGCLSNLHDSSHK--QRKKVIMQAFSREALQCYVPVIAEEVSSCLEQWLSCGE 172
            ......:|..||.|.|.:   :.||  .|:|.:..||....||.::.:..||   | :::|:..|
  Fly   117 NVVYELIRPFLGDGLLIS---TDHKWHSRRKALTPAFHFNVLQSFLGIFKEE---C-KKFLNVLE 174

Mouse   173 RGLLVYPEVKRLMFRIAMRIL----LGCEPGPAGGGEDEQQLVEAFEEMTRNLFSLPIDVPFS-- 231
            :.|....|:.:::....:..:    ||.:......|.:.::.:.|.||:.......|: :.::
  Fly   175 KNLDAELELNQVIPPFTLNNICETALGVKLDDMSEGNEYRKAIHAIEEVLIQRVCNPL-MYYNWY 238

Mouse   232 ----GLYR-GVKARNLIH---ARIEENIRAKIRRLQATEPDG-GCKD---ALQLLIEHSWERGER 284
                |.|| .::...::|   :||.|..|.:.::.|..|.|. |.|.   .|..|:  :.|...:
  Fly   239 FFVYGDYRKHLQNLRIVHDFSSRIIERKRQQFQQKQLGEVDEFGRKQRYAMLDTLL--AAEADGQ 301

Mouse   285 LDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREEIKSKGLLCKSNQDNKLDMET 349
            :|.|.:.......:|.|::||::.....:..|.|:..|.:|..||:::   |.:.:.|  :.|..
  Fly   302 IDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEVEN---LPEDSDD--ISMFQ 361

Mouse   350 LEQLKYTGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVADIFTNKEEF 414
            ..:|.|..|||||:||:.|.||...|..::...:||..:||...:...|.|.......|...:.|
  Fly   362 FNKLVYLECVIKESLRMFPSVPFIGRQCVEETVVNGMVMPKDTQISIHIYDIMRDPRHFPKPDLF 426

Mouse   415 NPDRFIVPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 462
            .||||:..:..:...|:::||..|.|:|:|::||.:.:|:....:.|:
  Fly   427 QPDRFLPENTVNRHPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRN 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp26a1	NP_031837.2	CYP26A1	55..490	CDD:410731	103/439 (23%)
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	99/413 (24%)