Protein Alignment Cyp24a1 and Cyp301a1

DIOPT Version :9

• Sequence 1: NP_034126.1
• Gene: Cyp24a1 / 13081
• MGIID: 88593
• Length: 514
• Species: Mus musculus
• Sequence 2: NP_610796.1
• Gene: Cyp301a1 / 36378
• FlyBaseID: FBgn0033753
• Length: 553
• Species: Drosophila melanogaster
• Alignment Length: 514
• Identity: 139/514 - (27%)
• Similarity: 232/514 - (45%)
• Gaps: 80/514 - (15%)

Mouse    31 KAHVKRAPKEVPLCPLMTDGETRNV---------------TSLPGPTNWPLLGS---LLEIFWKG 77
            :|..:.:...|..||.:.|.|..:.               ..:|||...|:||:   |:.|..:.
  Fly    33 RAQCRESSTGVATCPHLADSEEASAPRIHSTSEWQNALPYNQIPGPKPIPILGNTWRLMPIIGQY 97

Mouse    78 GLKKQHDTLAEYHKKYGQIFRMKLGSFDSVHLGSPSLL--------EALYRTESAHPQRLEIKPW 134
            .:.......:..|.:||:|.|     |..: :|.|.||        |..||:|...|.|..:...
  Fly    98 TISDVAKISSLLHDRYGRIVR-----FGGL-IGRPDLLFIYDADEIEKCYRSEGPTPFRPSMPSL 156

Mouse   135 KAY-----RDHRNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIMKLDKKINEVLADFMGQIDELR 194
            ..|     :|...:..|::.:.|:.|:..||..||.:::...|.:..:.:..:..||:.:.:.|.
  Fly   157 VKYKSVVRKDFFGDLGGVVGVHGEPWREFRSRVQKPVLQLSTIRRYLQPLEVITEDFLVRCENLL 221

Mouse   195 DERGRI-QDLYSELNKWSFESICLVLYEKRFGLLQKD--TEEEALTFIAAIKTMMSTFGKMMVTP 256
            ||...: :|..:|::|||.|.|..|..:.|.|.|:.:  .:.|....|.|.|..:.....:
  Fly   222 DENQELPEDFDNEIHKWSLECIGRVALDTRLGCLESNLKPDSEPQQIIDAAKYALRNVATL---- 282

Mouse   257 VELHKRLNTKVWQAH-TLAWDTIFKS----VKPCIDH------RLERYSQQP----GADFLCD-- 304
                 .|....|:.. |..|....|:    |..|:.:      ||:  :|.|    |...|.:
  Fly   283 -----ELKAPYWRYFPTPLWTRYVKNMNFFVGVCMKYIQSATERLK--TQDPSLRAGEPSLVEKV 340

Mouse   305 IYQQDHLSKKELYAAV--TELQLAAVETTANSLMWILYNLSRNPQVQQRLLREIQSVLPDNQTPR 367
            |..|    |.|..|.:  .:|.|..::|.:.::..:||.|:..|..||::..|::.:|||..||.
  Fly   341 ILSQ----KDEKIATIMALDLILVGIDTISMAVCSMLYQLATRPVDQQKVHEELKRLLPDPNTPL 401

Mouse   368 AEDVRN-MPYLKACLKESMRLTPSVPFTTRTLDKPTVLGEYTLPKGTVLTLNTQVLGSSEDNFED 431
            ...:.: |.:||..:||..|:..:|....|||.:.:|:..|.:|||......|.|.|:.|:...|
  Fly   402 TIPLLDQMHHLKGFIKEVFRMYSTVIGNGRTLMEDSVICGYQVPKGVQAVFPTIVTGNMEEYVTD 466

Mouse   432 ADKFRPERWLEKEK-----KINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIIQKYNI 485
            |..|||||||:.:.     |::|||.||:|.|.|||:|||.|:|::.:.|..:::.|.:
  Fly   467 AATFRPERWLKPQHGGTPGKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKL 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp24a1	NP_034126.1	p450	59..513	CDD:278495	133/471 (28%)
Cyp301a1	NP_610796.1	p450	76..530	CDD:299894	133/471 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	190	1.000	Domainoid score	I3255
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	196	1.000	Inparanoid score	I3800
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	1	1.000	-	-		mtm8705
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.870