Protein Alignment Cyp19a1 and Cyp4p2

DIOPT Version :9

• Sequence 1: NP_001335100.1
• Gene: Cyp19a1 / 13075
• MGIID: 88587
• Length: 503
• Species: Mus musculus
• Sequence 2: NP_610472.1
• Gene: Cyp4p2 / 35946
• FlyBaseID: FBgn0033395
• Length: 520
• Species: Drosophila melanogaster
• Alignment Length: 455
• Identity: 106/455 - (23%)
• Similarity: 183/455 - (40%)
• Gaps: 133/455 - (29%)

Mouse    90 SGEETLIISKSSSMFHV---------MKHSHYISRFGSKRGLQCIGMHENGIIFN-NNPSL---- 140
            ||:..|..|...|.|:|         :.|.:.|::               |:|:| .:|.|
  Fly    82 SGDSYLQYSMGFSNFNVIDAHNAANILNHPNLITK---------------GVIYNFLHPFLRTGV 131

Mouse   141 -------WRTIRPFFMKALTGPGLVRMVEVCVESIKQHLDRLGE-----VTDTSGYVD------- 186
                   |.|.|....:..                  |||.|.:     :.::..:|.
  Fly   132 LTATEKKWHTRRSMLTRTF------------------HLDILNQFQEIFIAESLKFVSQFQGQNE 178

Mouse   187 -VLTLMRHIMLDTSNML---FLGIPLDESAIVKKIQGYFNAWQAL-------LIKPNIFFKISW- 239
             |::|...|...|.|.:   .:||.|||.|  :|...|...:..:       ::.|     :.|
  Fly   179 VVVSLKDRISRFTLNSICETAMGIKLDEMA--EKGDRYRANFHIIDEGLTRRIVNP-----LYWD 236

Mouse   240 --LY-----RKYERSVKDLKDEIAVLVEKKRHKVSTAEKLED-----------CM----DFA--T 280
              :|     .||..::|.:.:....::.|:|  |...|:||:           |:    .||  .
  Fly   237 DCVYNMFTGHKYNAALKVVHEFSREIIAKRR--VLLEEELENRRATQTADDDICVIRKKRFAMLD 299

Mouse   281 DLIFAERRGDLTKENVNQCILEMLIAAPDTMSVTLYF----MLLLVAE----YPEVEAAILKEIH 337
            .||.||:.|.:....:::.:..::....||.|:.|.|    |.|..||    |.|::..||.::
  Fly   300 TLICAEKDGLIDDIGISEEVDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEHILDDL- 363

Mouse   338 TVVGDRDIKIEDIQNLKVVENFINESMRYQPVVDLVMRRAL-EDDVIDGYPVKKGTNIILNIGRM 401
                 .::.:..:..|..:..||.|:||..|.:.::.|:.| |.::.:|..:.|.:.|.:::..:
  Fly   364 -----SNLNLSQLSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINIHVFDI 423

Mouse   402 HR-LEYFPKPNEFTLENF-----EKNVPYRYFQPFGFGPRGCAGKYIAMVMMKVVLVTLLRRFQV 460
            || .:|:..|.||..|.|     .|..||.|. ||..|.|.|.|:..||..||.::|.:|:.|::
  Fly   424 HRNPKYWESPEEFRPERFLPQNCLKRHPYAYI-PFSAGQRNCIGQKYAMQEMKTLMVVILKHFKI 487

Mouse   461  460
              Fly   488  487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp19a1	NP_001335100.1	p450	48..488	CDD:306555	106/455 (23%)
Cyp4p2	NP_610472.1	p450	63..514	CDD:299894	106/455 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845359
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.040