Protein Alignment Cyp19a1 and Cyp4ac3

DIOPT Version :9

• Sequence 1: NP_001335100.1
• Gene: Cyp19a1 / 13075
• MGIID: 88587
• Length: 503
• Species: Mus musculus
• Sequence 2: NP_608918.1
• Gene: Cyp4ac3 / 33756
• FlyBaseID: FBgn0031695
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 382
• Identity: 91/382 - (23%)
• Similarity: 176/382 - (46%)
• Gaps: 40/382 - (10%)

Mouse   141 WRTIRPFFMKALTGPGLVRMVEVCVESIKQHLDRLGEVTDTS-GY-VDVLTLMRHIMLDTSNMLF 203
            |.|.|    |.||......:::..:...|:...:..::.|.: |: :::..::....|:......
  Fly   139 WHTRR----KTLTPAFHFNILQSFLSIFKEESKKFIKILDKNVGFELELNQIIPQFTLNNICETA 199

Mouse   204 LGIPLDE----SAIVKKIQGYFNAWQALLIKPNIFFKISWL------YRKYERSVKDLKDEIAVL 258
            ||:.||:    :...|.|..:...:...:..|.:||  :|.      |:||.|.::.:....:.:
  Fly   200 LGVKLDDMSEGNEYRKAIHDFEIVFNQRMCNPLMFF--NWYFFLFGDYKKYSRILRTIHGFSSGI 262

Mouse   259 VEKKRHKVSTAEKLEDCMDFA--------TDLIFAERRGDLTKENVNQCILEMLIAAPDTMSVTL 315
            :::||.:.. .::|....:|.        ..|:.||..|.:..:.:...:...:....||.|.:|
  Fly   263 IQRKRQQFK-QKQLGQVDEFGKKQRYAMLDTLLAAEAEGKIDHQGICDEVNTFMFGGYDTTSTSL 326

Mouse   316 YFMLLLVAEYPEVEAAILKEIHTVVGDRD-IKIEDIQNLKVVENFINESMRYQPVVDLVMRRALE 379
            .|.|||:|.:.:|:....:|:..:..|.| :.:.....|..:|..|.||:|..|...::.|..:|
  Fly   327 IFTLLLLALHADVQERCYEELQDLPEDIDEVSMFQFNELIHLECVIKESLRLFPSAPIIGRTCIE 391

Mouse   380 DDVIDGYPVKKGTNIILNI-GRMHRLEYFPKPNEFTLENF--EKNV---PYRYFQPFGFGPRGCA 438
            :.|::|..:.|...|.::| ..|....:|||||:|..|.|  |.:|   |:. |.||..|||.|.
  Fly   392 ESVMNGLVLPKNAQISIHIYDIMRDARHFPKPNQFLPERFLPENSVNRHPFA-FVPFSAGPRNCI 455

Mouse   439 GKYIAMVMMKVVLVTLLRRFQVKTLQKRCIENIPKKNDLSLHPNEDRHLVEIIFSPR 495
            |:...::.:||:|..::|.|  |.|....:|::..:|.:.|...::   :::.|..|
  Fly   456 GQKFGVLEIKVLLAAVIRNF--KLLPATQLEDLTFENGIVLRTQQN---IKVKFEAR 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp19a1	NP_001335100.1	p450	48..488	CDD:306555	89/373 (24%)
Cyp4ac3	NP_608918.1	p450	51..504	CDD:278495	89/377 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845356
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.040