Protein Alignment Cyp11b2 and Cyp12e1

DIOPT Version :9

• Sequence 1: NP_034121.4
• Gene: Cyp11b2 / 13072
• MGIID: 88584
• Length: 500
• Species: Mus musculus
• Sequence 2: NP_650003.4
• Gene: Cyp12e1 / 41272
• FlyBaseID: FBgn0037817
• Length: 522
• Species: Drosophila melanogaster
• Alignment Length: 544
• Identity: 136/544 - (25%)
• Similarity: 233/544 - (42%)
• Gaps: 96/544 - (17%)

Mouse    11 LARPW--------QCLHRTRALGTTATLAP-KTLQPFEAIPQYSRNKWLKMIQILRE--QGQENL 64
            |:..|        |.....|.|...||... :..:|:..||..|:      :|::|.  .|....
  Fly     2 LSTQWNANKQISRQIYQLCRGLAQKATAVNLEEAKPYADIPGPSK------LQLIRAFLPGGLYK 60

Mouse    65 HLEMHQVF----RELGPIFR-HSVGKTQIVSVMLPEDAEKLHQVESMLPRRMHLEPW-----VAH 119
            :|.:|::|    |:.|.||| .||..|.:|..|.|:|.|.:.:.|...|.|...|..     |..
  Fly    61 NLPVHEMFLDMNRQYGSIFRMPSVAGTDLVLTMNPQDYEVIFRNEGQYPYRRSFEVMDYFKRVHR 125

Mouse   120 REL----RGLRRGVFLLNGPEWRLNRLRLNRNVLSPKAVQKFVPMVDMVARDFLE---TLKEKVL 177
            ||:    .||..|    |||.|...|..:|..:|.|:..:.::..:..|:.:|||   .:::.|.
  Fly   126 REVFDGYDGLTSG----NGPAWGKMRTAVNPILLQPRNAKLYMTNLVQVSDEFLERIRIIRDPVT 186

Mouse   178 QNARGSLTMDVQQSLFNYTIEASNFALFGERLGLLGHDLSPGSL-KFIHALHSMFKSTSQLLFLP 241
            |.......:|::    :..||:.........|||||...:...: |.:.||..:.:...||..:|
  Fly   187 QEMPDDFAVDIR----HLVIESICSVALNTHLGLLGEQRNNKDIQKLVLALQDVVELGFQLDIMP 247

Mouse   242 KSLTRWTSTRVWKEHFDAWDVISEYANRCIWKVHQELRLGSSQTYSGIVAELISQGSLPLDAIKA 306
             :..::.....:|:...:.|.|:::   |.:.:...|:.......:|.:.|:..:.||.....:.
  Fly   248 -AFWKYLPMPNFKKLMRSLDTITDF---CYFHIGNALKRIEEDAKAGTLNEIGLETSLLEKLARF 308

Mouse   307 N-------SMELTAGSVDTTAIPLVMTLFELARNPDVQKALRQE----------SLAAEASIAAN 354
            :       :|:|.....|.|.:.|...||.|:::||.|..|.:|          ||..|
  Fly   309 DRQTAVIIAMDLLFAGADPTLVTLGGILFSLSKSPDKQARLLEEIRGILPNKDSSLTIE------ 367

Mouse   355 PQKAMSDLPLLRAALKETLRLYPVGGFLERILSSDLVLQNYHVPAGTLV-LLYLYSMGRNPAVFP 418
               .|.:||.|||.:||.:|:||:|....|.:..|:||..|.|.|||.| :...|.|.......|
  Fly   368 ---NMRNLPYLRACIKEGIRMYPIGPGTLRRMPHDVVLSGYRVVAGTDVGIAANYQMANMEQFVP 429

Mouse   419 RPERYMPQRWL----------ERKRSFQHLAFGFGVRQCLGRRLAEVEMMLLLHHILKTFQV--- 470
            :...::|:|||          |....|.:|.||||.|.|.|:|:.::.:.:.:..:::.|::
  Fly   430 KVREFIPERWLRDESNSHLVGETATPFMYLPFGFGPRSCAGKRIVDMMLEIAISRLVRNFKIGFD 494

Mouse   471 ---------ETLRQEDVQMAYRFV 485
                     :...|.::...::|:
  Fly   495 YPIENAFKAQFFVQPNIPFKFKFI 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp11b2	NP_034121.4	p450	42..496	CDD:365848	127/504 (25%)
Cyp12e1	NP_650003.4	p450	63..517	CDD:299894	120/474 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8705
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920